A student looking at microscopic image on screen
Analysing the results of an experiment
(Image Credit: Rob Judges / Oxford University Images)

DPhil in Physiology, Anatomy and Genetics

About the course

The DPhil (a PhD at other universities) in Physiology, Anatomy and Genetics offers a wide range of research topics within a large multi-disciplinary and world-renowned department, spanning a diverse spectrum of research.

Research in the department is organised around six major themes:

  • cardiac science
  • development and reproduction
  • functional genomics
  • ion channels, transporters and signalling
  • metabolism and endocrinology
  • neuroscience

Within each of these themes there are several research groups and centres. All staff and doctoral students belong to one or more of these research groups, each of which has its own seminar programme to which graduate students often contribute. In addition, the department as a whole sponsors regular seminars and public lectures which attract distinguished national and international speakers.

In the first instance, applicants are advised to identify potential supervisors in Physiology, Anatomy and Genetics, based on their research area of interest. You will then nominate a supervisor on the application form together with the agreed research project title. As science advances, projects may or may not change.

You will conduct research at Oxford under the supervision of academic staff who are at the forefront of developments in your chosen research project area. You will explore your research subject area to new depths and have the opportunity to present your findings to members of the international scientific community with whom, one day, you may well collaborate. 

After attending the new graduate students’ induction day, you will meet your supervisor and fellow group members. You will complete an Analysis of your Training Needs (TNA) with your supervisor and then attend any training courses from the divisional flexible skills training programme which you will need in your research project. The courses on the toolkit include a range of workshops and seminars in transferable skills, generic research skills and specific research techniques which may be pertinent to your DPhil research area. You will have access to regular departmental seminars and peer presentation groups for fine tuning presentation deliverance alongside graduate student social events which incorporate informal talks aimed at students. Examples are Public Speaking and Securing Your First Postdoc Job, Careers, Poster Presentation and from seminars talks in various themes from eminent worldwide scientists, to talks on local research being conducted in the department. Special lectures are given to recognise previous famous scientists of the department and will vary in subject.

You will be encouraged to submit termly reports on your progress and report courses undertaken. Your supervisor will also contribute to your termly reports.

Students are encouraged to volunteer as one of several student representatives in their second year of study, to sit on various committees, to host seminar speakers and to arrange student social events.

Attendance

The course is full-time and requires attendance in Oxford. Full-time students are subject to the University's Residence requirements.

Provision exists for students on some courses to undertake their research in a ‘well-founded laboratory’ outside of the University. This may require travel to and attendance at a site that is not located in Oxford. Where known, existing collaborations will be outlined on this page. Please read the course information carefully, including the additional information about course fees and costs. 

Resources to support your study

As a graduate student, you will have access to the University's wide range of world-class resources including libraries, museums, galleries, digital resources and IT services.

The Bodleian Libraries is the largest library system in the UK. It includes the main Bodleian Library and libraries across Oxford, including major research libraries and faculty, department and institute libraries. Together, the Libraries hold more than 13 million printed items, provide access to e-journals, and contain outstanding special collections including rare books and manuscripts, classical papyri, maps, music, art and printed ephemera.

The University's IT Services is available to all students to support with core university IT systems and tools, as well as many other services and facilities. IT Services also offers a range of IT learning courses for students, to support with learning and research.

DPAG IT Services provides various services to the department. These include e-mail, network file storage, computer and printer management services, and maintenance of the network both wired and wireless across the departmental estate.

The Radcliffe Science Library provides a print collection of books, journals and statistics. In addition, it provides access to a wide range of electronic resources.

Supervision

Applicants are encouraged to communicate with potential supervisors prior to submitting an application to agree the research topic proposed by the applicant.

The allocation of graduate supervision is the responsibility of the Department of Physiology, Anatomy & Genetics and it is not always possible to accommodate the preferences of incoming graduate students to work with a particular member of staff. Under exceptional circumstances a supervisor may be found outside the Department of Physiology, Anatomy and Genetics.

Most students have the opportunity to formally meet with their supervisors on a monthly basis while informal meetings are encouraged and may occur more frequently concerning the science.

All students in the Medical Sciences Division are required to have a co-supervisor in place once the programme of study is underway.

Assessment

At the end of your first year or start of the second year, you will prepare and undertake the first milestone, Transfer of Status from Probationer Research Student (PRS) status to DPhil status, for which you will submit a written report describing your research to date and plans for the future. This will be assessed by two independent experts, who interview you as part of the process. The Transfer of Status milestone is generally undertaken towards the end of the third term and no later than the fourth term of the programme. At this point of the programme, you should have established relevant methodology and collected some preliminary data.

When you successfully pass the Transfer of Status, your next milestone is Confirmation of Status which will be no later than your ninth term (end of third year). At the Confirmation of Status, you give a full thesis outline and timeline within the application, then at the Confirmation viva, you will give a presentation to outline everything you have completed to date that will be in your thesis. The Confirmation of Status assessment is appraised by two experts. Subject to confirming your status, you will then write up your thesis for submission and defend the thesis at your Viva Voce examination. The Confirmation of Status milestone is generally undertaken from the eighth term on course and no later than the ninth term of the programme.

Graduate destinations

An alumni survey showed nearly two-thirds were employed in academic research or had returned to medicine in conjunction with academic research. Other careers included industrial research, high-tech start up companies, financial and business sectors, pharmaceutical consulting, teaching, scientific publishing, patent law and banking with some entering charitable fund raising and charitable scientific employment. 

Changes to this course and your supervision

The University will seek to deliver this course in accordance with the description set out in this course page. However, there may be situations in which it is desirable or necessary for the University to make changes in course provision, either before or after registration. The safety of students, staff and visitors is paramount and major changes to delivery or services may have to be made if a pandemic, epidemic or local health emergency occurs. In addition, in certain circumstances, for example due to visa difficulties or because the health needs of students cannot be met, it may be necessary to make adjustments to course requirements for international study.

Where possible your academic supervisor will not change for the duration of your course. However, it may be necessary to assign a new academic supervisor during the course of study or before registration for reasons which might include illness, sabbatical leave, parental leave or change in employment.

For further information please see our page on changes to courses and the provisions of the student contract regarding changes to courses.

Entry requirements for entry in 2025-26

Proven and potential academic excellence

The requirements described below are specific to this course and apply only in the year of entry that is shown. You can use our interactive tool to help you evaluate whether your application is likely to be competitive.

We know that factors such as socio-economic circumstances and school performance can make it difficult for students to demonstrate their full potential. This course is taking part in an initiative to use contextual data to help us to better understand your achievements in the context of your individual background. For further details, please refer to the information about improving access to graduate study in the How to apply section of this page.

Please be aware that any studentships that are linked to this course may have different or additional requirements and you should read any studentship information carefully before applying. Contextual data may also be used in the assessment of studentships. 

Degree-level qualifications

As a minimum, applicants should hold or be predicted to achieve the following UK qualifications or their equivalent:

  • a first-class or strong upper second-class undergraduate degree with honours in a subject that ideally will support the chosen research path.

A previous master's degree is not a condition of entry.

For applicants with a degree from the USA, the minimum overall GPA that is normally required to meet the undergraduate-level requirement is 3.5 out of 4.0.

If your degree is not from the UK or another country specified above, visit our International Qualifications page for guidance on the qualifications and grades that would usually be considered to meet the University’s minimum entry requirements.

GRE General Test scores

No Graduate Record Examination (GRE) or GMAT scores are sought.

Other qualifications, evidence of excellence and relevant experience

  • Publication links should be included within the CV/résumé if applicable.
  • It would be expected that graduate applicants would be familiar with the recent published work of their proposed supervisor.

English language proficiency

This course requires proficiency in English at the University's higher level. If your first language is not English, you may need to provide evidence that you meet this requirement. The minimum scores required to meet the University's higher level are detailed in the table below.

Minimum scores required to meet the University's higher level requirement
TestMinimum overall scoreMinimum score per component
IELTS Academic (Institution code: 0713) 7.57.0

TOEFL iBT, including the 'Home Edition'

(Institution code: 0490)

110Listening: 22
Reading: 24
Speaking: 25
Writing: 24
C1 Advanced*191185
C2 Proficiency191185

*Previously known as the Cambridge Certificate of Advanced English or Cambridge English: Advanced (CAE)
Previously known as the Cambridge Certificate of Proficiency in English or Cambridge English: Proficiency (CPE)

Your test must have been taken no more than two years before the start date of your course. Our Application Guide provides further information about the English language test requirement.

Declaring extenuating circumstances

If your ability to meet the entry requirements has been affected by the COVID-19 pandemic (eg you were awarded an unclassified/ungraded degree) or any other exceptional personal circumstance (eg other illness or bereavement), please refer to the guidance on extenuating circumstances in the Application Guide for information about how to declare this so that your application can be considered appropriately.

References

You will need to register three referees who can give an informed view of your academic ability and suitability for the course. The How to apply section of this page provides details of the types of reference that are required in support of your application for this course and how these will be assessed.

Supporting documents

You will be required to supply supporting documents with your application. The How to apply section of this page provides details of the supporting documents that are required as part of your application for this course and how these will be assessed.

Performance at interview

Interviews are held as part of the admissions process and take place in January for entry in October of the same year. All shortlisted candidates called to interview will have been assessed on completed applications only. Funded places are awarded purely on the basis of an assessment of candidates' excellence appropriate to their intended research path.

Offer conditions for successful applications

If you receive an offer of a place at Oxford, your offer will outline any conditions that you need to satisfy and any actions you need to take, together with any associated deadlines. These may include academic conditions, such as achieving a specific final grade in your current degree course. These conditions will usually depend on your individual academic circumstances and may vary between applicants. Our 'After you apply' pages provide more information about offers and conditions

In addition to any academic conditions which are set, you will also be required to meet the following requirements:

Financial Declaration

If you are offered a place, you will be required to complete a Financial Declaration in order to meet your financial condition of admission.

Disclosure of criminal convictions

In accordance with the University’s obligations towards students and staff, we will ask you to declare any relevant, unspent criminal convictions before you can take up a place at Oxford.

Academic Technology Approval Scheme (ATAS)

Some postgraduate research students in science, engineering and technology subjects will need an Academic Technology Approval Scheme (ATAS) certificate prior to applying for a Student visa (under the Student Route). For some courses, the requirement to apply for an ATAS certificate may depend on your research area.

Other factors governing whether places can be offered

The following factors will also govern whether candidates can be offered places:

  • the ability of the University to provide the appropriate supervision for your studies, as outlined under the 'Supervision' heading in the About section of this page;
  • the ability of the University to provide appropriate support for your studies (eg through the provision of facilities, resources, teaching and/or research opportunities); and
  • minimum and maximum limits to the numbers of students who may be admitted to the University's taught and research programmes.

Physiology, Anatomy & Genetics

The Department of Physiology, Anatomy and Genetics (DPAG) is a major basic-science department within the Division of Medical Sciences.

Ranked number one in Anatomy and Physiology in the world according to the QS World University Rankings 2024, the department has excellent facilities for the large number of full-time research students who are fully integrated into the research of the department.

The department offers courses in an extraordinarily wide range of specialised and interdisciplinary topics, including molecular, cellular and integrative neuroscience, cardiovascular physiology, cellular and whole-body metabolism, functional genomics, neurobiology of sleep and circadian rhythms.

DPAG is home to a large number of internationally-renowned teams of scientists addressing major questions in biomedicine, the answers to which will have a profound effect on modern biology. Crucially, DPAG thinks learning is just as important as research, and at the department's core lies a belief that a synthesis of the two is key to advancing our understanding. As such, DPAG works to provide outstanding opportunities for graduate students to enjoy cutting-edge training across a diverse range of state-of-the-art methodologies in leading laboratories in the field, to develop practical skills to excel in academia, industry, consulting, high-tech start-ups and have made outstanding achievements in a variety of career fields; from making ground-breaking discoveries into fundamental biological processes to translational contributions with real-life impacts.

Since the department's work is multidisciplinary and cross-cutting, researchers often work across more than one theme, as well as collaborating with colleagues in the physical sciences, life sciences and clinical departments across Oxford and elsewhere. It is hoped, the postgraduate students’ experiences in DPAG will help them to become the leaders in science of tomorrow, to communicate and employ their research in the wider world.

In parallel to research, DPAG staff undertake the majority of the pre-clinical teaching for the University's top-ranked medical degrees while the department's graduate courses also attract a wealth of international talent. Ultimately, the department is built on a desire to understand – its scientific research areas with a belief its students are the future of research.

Funding

For entry in the 2025-26 academic year, the collegiate University expects to offer over 1,000 full or partial graduate scholarships across a wide range of graduate courses.

If you apply by the December deadline shown on this page and receive a course offer, your application will then be considered for Oxford scholarships. For the majority of Oxford scholarships, your application will automatically be assessed against the eligibility criteria, without needing to make a separate application. There are further Oxford scholarships available which have additional eligibility criteria and where you are required to submit a separate application. Most scholarships are awarded on the basis of academic merit and/or potential.

To ensure that you are considered for Oxford scholarships that require a separate application, for which you may be eligible, use our fees, funding and scholarship search tool to identify these opportunities and find out how to apply. Alongside Oxford scholarships, you should also consider other opportunities for which you may be eligible including a range of external fundingloan schemes for postgraduate study and any other scholarships which may also still be available after the December deadline as listed on our fees, funding and scholarship search tool.

Details of college-specific funding opportunities can also be found on individual college websites:

Please refer to the College preference section of this page to identify which of the colleges listed above accept students for this course.

For the majority of college scholarships, it doesn’t matter which college, if any, you state a preference for in your application. If another college is able to offer you a scholarship, your application can be moved to that college if you accept the scholarship. Some college scholarships may require you to state a preference for that college when you apply, so check the eligibility requirements carefully.

Costs

Annual fees for entry in 2025-26

Fee status

Annual Course fees

Home£10,070
Overseas£33,370

Information about course fees

Course fees are payable each year, for the duration of your fee liability (your fee liability is the length of time for which you are required to pay course fees). For courses lasting longer than one year, please be aware that fees will usually increase annually. For details, please see our guidance on changes to fees and charges.

Course fees cover your teaching as well as other academic services and facilities provided to support your studies. Unless specified in the additional information section below, course fees do not cover your accommodation, residential costs or other living costs. They also don’t cover any additional costs and charges that are outlined in the additional information below.

Continuation charges

Following the period of fee liability, you may also be required to pay a University continuation charge and a college continuation charge. The University and college continuation charges are shown on the Continuation charges page.

Where can I find further information about fees?

The Fees and Funding section of this website provides further information about course fees, including information about fee status and eligibility and your length of fee liability.

Additional information

There are no compulsory elements of this course that entail additional costs beyond fees (or, after fee liability ends, continuation charges) and living costs. However, please note that, depending on your choice of research topic and the research required to complete it, you may incur additional expenses, such as travel expenses, research expenses, and field trips. You will need to meet these additional costs, although you may be able to apply for small grants from your department and/or college to help you cover some of these expenses.

Living costs

In addition to your course fees and any additional course-specific costs, you will need to ensure that you have adequate funds to support your living costs for the duration of your course.

Living costs for full-time study

For the 2025-26 academic year, the range of likely living costs for a single, full-time student is between £1,425 and £2,035 for each month spent in Oxford. We provide the cost per month so you can multiply up by the number of months you expect to live in Oxford. Depending on your circumstances, you may also need to budget for the costs of a student visa and immigration health surcharge and/or living costs for family members or other dependants that you plan to bring with you to Oxford (assuming that dependant visa eligibility criteria are met).

Further information about living costs

The current economic climate and high national rate of inflation make it very hard to estimate potential changes to the cost of living over the next few years. For study in Oxford beyond the 2025-26 academic year, it is suggested that you budget for potential increases in living expenses of around 4% each year – although this rate may vary depending on the national economic situation. For further information, please consult our more detailed information about living costs, which includes a breakdown of likely living costs in Oxford for items such as food, accommodation and study costs.

College preference

Students enrolled on this course will belong to both a department/faculty and a college. Please note that ‘college’ and ‘colleges’ refers to all 43 of the University’s colleges, including those designated as societies and permanent private halls (PPHs). 

If you apply for a place on this course you will have the option to express a preference for one of the colleges listed below, or you can ask us to find a college for you. Before deciding, we suggest that you read our brief introduction to the college system at Oxford and our advice about expressing a college preference

If you are a current Oxford student and you would like to remain at your current Oxford college, you should check whether it is listed below. If it is, you should indicate this preference when you apply. If not, you should contact your college office to ask whether they would be willing to make an exception. Further information about staying at your current college can be found in our Application Guide. 

The following colleges accept students on the DPhil in Physiology, Anatomy and Genetics:

Before you apply

Before you begin an application, we recommend that you consult the Medical Sciences Graduate School's website to identify the most suitable course for your intended area of research.

Our guide to getting started provides general advice on how to prepare for and start your application.  You can use our interactive tool to help you evaluate whether your application is likely to be competitive.

If it is important for you to have your application considered under a particular deadline – eg under the December deadline in order to be considered for Oxford scholarships – we recommend that you aim to complete and submit your application at least two weeks in advance. Check the deadlines on this page and the information about deadlines and when to apply in our Application Guide.

Application fee waivers

An application fee of £20 is payable for each application to this course. Application fee waivers are available for the following applicants who meet the eligibility criteria:

  • applicants from low-income countries;
  • refugees and displaced persons; 
  • UK applicants from low-income backgrounds; and 
  • applicants who applied for our Graduate Access Programmes in the past two years and met the eligibility criteria.

You are encouraged to check whether you're eligible for an application fee waiver before you apply.

Readmission for current Oxford graduate taught students

If you're currently studying for an Oxford graduate taught course and apply to this course with no break in your studies, you may be eligible to apply to this course as a readmission applicant. The application fee will be waived for an eligible application of this type. Check whether you're eligible to apply for readmission.

Application fee waivers for eligible associated courses

If you apply to this course and are considering applying (or have already applied) to any of the associated courses listed below, you can request an application fee waiver so that you only need to pay one application fee. We recommend that you use your application fee waiver to apply only for eligible courses that are closely related in research area to this one.

For full details about how to request an application fee waiver, please select the course you are interested in from the list below and refer to the equivalent section of its course page.

The following associated courses are taking part in this application fee waiver scheme:

Do I need to contact anyone before I apply?

You are advised to make enquiries as soon as possible prior to your intended date of entry, ideally before the December application deadline. 

Before applying you are strongly encouraged to identify areas of interest to you from the DPAG research pages and then directly contact the Principal Investigator ('Group Leader') to discuss the possibility of joining their group.

Applicants are expected to have communicated with their proposed research supervisor and to have agreed a research project with the full support of said supervisor before submitting an application. Communications are encouraged either in person or via Microsoft Teams, Zoom or Skype. 

Improving access to graduate study

This course is taking part in initiatives to improve the selection procedure for graduate applications, to ensure that all candidates are evaluated fairly.

Socio-economic data (where it has been provided in the application form) will be used as part of an initiative to contextualise applications at the different stages of the selection process.

Completing your application

You should refer to the information below when completing the application form, paying attention to the specific requirements for the supporting documents.

For this course, the application form will include questions that collect information that would usually be included in a CV/résumé. You should not upload a separate document. If a separate CV/résumé is uploaded, it will be removed from your application.

If any document does not meet the specification, including the stipulated word count, your application may be considered incomplete and not assessed by the academic department. Expand each section to show further details.

Proposed field and title of research project

You must enter the project you are applying to under 'Field and title of research project' on the 'Course' tab of the application form.

You should not use this field to type out a full research proposal. You will be able to upload your research supporting materials separately if they are required (as described below).

Proposed supervisor

Under 'Proposed supervisor name' enter the name of the academic(s) whom you would like to supervise your research. 

Referees:
Three overall, academic preferred

Whilst you must register three referees, the department may start the assessment of your application if two of the three references are submitted by the course deadline and your application is otherwise complete. Please note that you may still be required to ensure your third referee supplies a reference for consideration.

References should generally be academic but one or more professional references should be submitted if you have been in research employment.

Your references will support intellectual ability, academic achievement, motivation and ability to work in a group.

Official transcript(s)

Your transcripts should give detailed information of the individual grades received in your university-level qualifications to date. You should only upload official documents issued by your institution and any transcript not in English should be accompanied by a certified translation.

More information about the transcript requirement is available in the Application Guide.

Statement of purpose/personal statement and research proposal:
A maximum of 500 words each

Your statement of purpose/personal statement and research proposal should be submitted as a single, combined document with clear subheadings. Please ensure that the word counts for each section are clearly visible in the document.

Statement of purpose/personal statement

You should provide a statement of your research interests, in English, describing how your background and research interests relate to the programme. If possible, please ensure that the word count is clearly displayed on the document.

It will be normal for students’ ideas and goals to change in some ways as they undertake their studies, but your personal statement will enable you to demonstrate your current interests and aspirations.

The statement should focus on academic or research-related achievements and interests rather than personal achievements and interests.

This will be assessed for:

  • your reasons for applying;
  • evidence of motivation for and understanding of the proposed area of study;
  • the ability to present a reasoned case in English;
  • capacity for sustained and focused work; and
  • understanding of problems in the area and ability to construct and defend an argument.

Research proposal

You should submit an outline of your proposed research, written in English, covering areas such as the background, relevant methodology and research aims.

Your research proposal should be designed in cooperation with your proposed supervisors. A list of supervisors offering projects, as well as suggested research proposals, will be available on the DPAG admissions webpage, although you are welcome to discuss alternative projects and/or supervisors.

The project proposal will be assessed for:

  • the coherence of the proposal
  • the originality of the project
  • evidence of motivation for and understanding of the proposed area of study
  • the feasibility of successfully completing the project in the time available for the course (a maximum of four years)
  • commitment to the subject, beyond the requirements of the degree course
  • preliminary knowledge of research techniques
  • reasoning ability.

It will be normal for your ideas subsequently to change as you investigate the evidence and develop your project. You should nevertheless make the best effort you can to demonstrate the extent of your research question, sources and method at this moment.

Your proposal should focus primarily on the research rather than purely on personal achievements, interests and aspirations.

Start or continue your application

You can start or return to an application using the relevant link below. As you complete the form, please refer to the requirements above and consult our Application Guide for advice.

Apply Continue application

After you've submitted your application

Your application (including the supporting documents outlined above) will be assessed against the entry requirements detailed on this course page. Whether or not you have secured funding will not be taken into consideration when your application is assessed. You can find out more about our shortlisting and selection process in our detailed guide to what happens next.

Find out how to manage your application after submission, using our Applicant Self-Service tool.

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