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Graduate

DPhil in Genomic Medicine and Statistics

Training potential future leaders in the application of genomics to advance human health, this course combines taught modules and lab rotations followed by doctoral research in functional, population, disease and clinical genomics.

Full time

Open
Upcoming application deadline for 2027-28 entry:
12:00 midday UK time on Tuesday 1 December 2026

Expected length
4 years
Expected start date
October 2027
English language level
Standard level required

Application deadlines

12:00 midday UK time

Final application deadline for entry in 2027-28

Oxford skyline with view of Radcliffe Camera and the University Church

About the course

The course aims to train and nurture future leaders in the application of genomics to advance human health. It will equip students with skill sets spanning experimental and analytical genomic science in order to realise the potential of genomics and practice the qualities of fair and inspiring leadership that we will instil during the course.

The course is hosted in the interdisciplinary environment of the Centre for Human Genetics (CHG), which hosts world-leading research groups in genomic analysis, functional genomics, bioinformatics, statistics, population genetics, translational genomics, protein structure and functional biology, together with outstanding disease-focused research including cardiovascular medicine, type 1 and type 2 diabetes, cancer genetics, immunity, inflammation and infectious disease.

United by common interests in understanding the molecular basis of disease, researchers come from clinical and pure science backgrounds. The CHG is part of the Nuffield Department of Medicine and closely linked with the clinical departments in the Oxford University Hospitals NHS Foundation Trust, providing unique opportunities for translation of research into clinical practice which is further enhanced by having the Oxford NIHR BRC Genomics Theme based within the CHG and the Centre for Personalised Medicine.  

The interdisciplinary nature of the CHG strongly encourages interactions between research groups, and the centre runs internal and high-profile external seminar series, journal clubs, away days, training in scientific communication, and social events, to enable such interactions on a frequent basis.

Co-located on the Old Road campus with the CHG and across the Medical Sciences Division (MSD) are complementary research institutes and key stakeholders for translation (NHS and industry) that together constitute a remarkable inter- disciplinary environment for genomics research and training. This includes expertise in immunology, infectious disease and cancer through the CAMS Oxford Institute and the Ludwig Institute for Cancer Research, and the analytical expertise of supervisors from the Big Data Institute and the Department of Statistics.

Supervisors from the Target Discovery Institute and Department of Chemistry have further highly complementary translational expertise, for example in proteomics, metabolomics and medicinal chemistry that reflect the necessary interdisciplinarity to translate the potential of genomics.

The course also includes leading scientists from the Weatherall Institute of Molecular Medicine in genome engineering, relevant model systems including stem cells, gene regulation and epigenetics. The translational application of genomics is being pioneered in Oxford, with supervisors in addition to those at the CHG in pathogen genomics, palaeogenomics as well as in clinical application spanning rare disease and intervention to effect cure using gene editing constituting some of the most advanced work worldwide in this area.

The NIHR Biomedical Research Centre supports collaboration with the NHS and active engagement with outstanding clinical trials units experienced in experimental studies and the Oxford NHS Genomic Medicine Centre further enriches this. Oxford has also a highly active entrepreneurial spirit where spin out companies are encouraged and supported alongside collaborations with established biotech and pharma. It is expected that there will be opportunities for internships.

This outstanding cross-disciplinary research environment is underpinned by the latest technologies, including sequencing and multiomics platforms, mass spectrometry, advanced microscopy, metabolomics and proteomics, single-cell deep phenotyping, preclinical model organism analyses, and one of the most advanced computing facilities in Europe.

The course actively seeks to recruit students from diverse academic and personal backgrounds, united by a track record of academic excellence and enthusiasm for this field. Students receive world-class training, supervision, and mentorship. Promoting excellence in research culture underlies all aspects of the programme with a commitment to support creativity, prioritise inclusivity, and promote best practices. Student feedback is recognised and valued, and we obtain it through various channels, including via direct feedback and via student representatives.

Course structure

This section provides an overview of the course structure, while details of the individual course components are provided below.

The first year of the course includes bespoke training focussed within the first term, combining theoretical and practical classes in a broad curriculum of genomic science, with further skills training available through the Nuffield Department of Medicine and the Medical Sciences Doctoral Training Centre throughout the course. 

The first term also includes dedicated time to meet with course PIs and start exploring potential rotation projects. You will also be invited to regular departmental seminars and we will encourage you to use these opportunities to begin forming the ideas and networks that will lead to your DPhil research.

First-year students then undertake short research project rotations in up to three laboratories, each lasting around three months, with further training tailored to the needs of students.

Lab rotations will be under the supervision of a named principal investigator. Workload involved is commensurate with full-time employment.

Towards the end of the first year, you will decide which laboratories and supervisor(s) you wish to work with and prepare a proposal for your three-year doctoral research project. There are opportunities to meet with potential supervisors from the start of the course and, in many cases, collaborative projects are proposed.

The final three years of the course will comprise doctoral research under the supervision of at least two named supervisors.

Core components

You will received research training in your first term.

Research areas

During years 2-4 you will undertake research within the specialised themes of this course.

Course details

Entry requirements

For entry in 2027-28

Funding and costs

College preference

Before you apply

Completing your application

Contact details