DPhil in Genomic Medicine and Statistics
About the course
This four-year DPhil programme aims to train and nurture future leaders in the application of genomics to advance human health. It will equip them with skill sets spanning experimental and analytical genomic science in order to realise the potential of genomics and practice the qualities of fair and inspiring leadership that we will instil during the course.
The first year includes taught modules focused within the first term. First-year students then undertake short research projects in up to three laboratories in three-month rotations, with further training and teaching sessions tailored to the needs of individual students. The research projects and lab visits help inform the choice of DPhil project to be undertaken over the subsequent three years of the programme. The final three years of the course will comprise doctoral research under the supervision of two named supervisors and a doctoral committee. Applicants are advised to visit the Doctoral Training Centre course webpage for further information about supervisors connected to this programme.
The programme actively seeks to recruit students from very diverse backgrounds, united by a track record of academic excellence and enthusiasm for this field. Students receive world-class training, supervision, mentorship and pastoral support. Promoting excellence in research culture underlies all aspects of the programme with a commitment to support creativity, prioritise diversity and inclusion, and promote best practice.
Module information
The programme is focused on the following themes:
- genomic and -omic technologies (including method development, single cell genomics, imaging, model systems, CRISPR screens, genome engineering, proteomics, metabolomics, high throughput screening)
- functional genomics (gene regulation and epigenetics)
- genome biology (genetic variation, recombination, human history, evolution, palaeogenomics, pathogen genomes)
- genomics of disease (Mendelian, multifactorial traits, cancer)
- genomic analysis (bioinformatics and statistical genetics)
- from genes to clinical proof of concept (integrated drug development pipeline spanning genetic-led target discovery, structural biology, medicinal chemistry)
- application of genomics in the clinic (rare disease diagnostics, cancer therapeutics, personalised medicine and genome therapies).
Teaching modules combine theoretical and practical classes, with further skills training available through the Medical Sciences Doctoral Training Centre.
Teaching and learning
The taught component of the course will be delivered by expert faculty including experienced principal investigators and postdoctoral scientists. Class sizes for taught modules will typically be between 5 and 20 students depending on format and content (median estimated at 12 students). Peer-to-peer and independent learning is also encouraged. Lab rotations will be under the supervision of a named principal investigator. Workload involved is commensurate with full time employment.
Training will be tailored to the individual needs of the student throughout the course. There will be opportunities for internships. Student feedback is recognised and valued. Mental health is a priority with a proactive approach to prevention, early recognition, peer and professional support. Bullying and harassment is prevented by promoting an encouraging and enabling culture with leadership by example and compulsory supervisor training. In addition to departmental membership, all students will be members of an Oxford college which further enhances interdisciplinarity, understanding of excellence in research culture, provision of outstanding pastoral and welfare support, and wider educational experience.
The programme is hosted in the interdisciplinary environment of the Centre for Human Genetics (CHG), which hosts world-leading research groups in genomic analysis, functional genomics, bioinformatics, statistics, population genetics, translational genomics, protein structure and functional biology, together with outstanding disease-focused research including cardiovascular medicine, type 1 and type 2 diabetes, cancer genetics, immunity, inflammation and infectious disease.
United by common interests in understanding the molecular basis of disease, researchers come from clinical and pure science backgrounds. The CHG is part of the Nuffield Department of Medicine and closely linked with the clinical departments in the Oxford University Hospitals NHS Foundation Trust, providing unique opportunities for translation of research into clinical practice which is further enhanced by having the Oxford NIHR BRC Genomics Theme based within the CHG and the Centre for Personalised Medicine.
The CHG has outstanding facilities including: omic technology platforms, computational genomics, biomedical research computing, cellular imaging, iPSCs and flow cytometry, all of which are available to support your research project.
The interdisciplinary nature of the CHG strongly encourages interactions between research groups, and the centre runs internal and high-profile external seminar series, retreats for students and post docs, journal clubs, away days, training in public engagement and communication skills, and social events, to enable such interactions on a frequent basis.
Co-located on the Old Road campus with the CHG and across the Medical Sciences Division (MSD) are complementary research institutes and key stakeholders for translation (NHS and industry) that together constitute a remarkable inter- disciplinary environment for genomics research and training.
This includes expertise in immunology, infectious disease and cancer through the CAMS Oxford Institute and the Ludwig Institute for Cancer Research, and the analytical expertise of supervisors from the Big Data Institute and the Department of Statistics. Supervisors from the Target Discovery Institute and Department of Chemistry have further highly complementary translational expertise, for example in proteomics, metabolomics and medicinal chemistry that reflect the necessary interdisciplinarity to translate the potential of genomics.
The course also includes leading scientists from the Weatherall Institute of Molecular Medicine in genome engineering, relevant model systems including stem cells, gene regulation and epigenetics. The translational application of genomics is being pioneered in Oxford, with supervisors in addition to those at the CHG in pathogen genomics, palaeogenomics as well as in clinical application spanning rare disease and intervention to effect cure using gene editing constituting some of the most advanced work worldwide in this area.
The NIHR Biomedical Research Centre supports collaboration with the NHS and active engagement with outstanding clinical trials units experienced in experimental studies and the Oxford NHS Genomic Medicine Centre further enriches this. Oxford has also a highly active entrepreneurial spirit where spin out companies are encouraged and supported alongside collaborations with established biotech and pharma.
This outstanding cross-disciplinary research environment is underpinned by the latest technologies, including mass spectrometry, advanced microscopy, metabolomics and proteomics, single-cell deep phenotyping, preclinical model organism analyses, and one of the most advanced computing facilities (based in the CHG) in Europe.
Attendance
The course is full-time and requires attendance in Oxford. Full-time students are subject to the University's Residence requirements.
Provision exists for students on some courses to undertake their research in a ‘well-founded laboratory’ outside of the University. This may require travel to and attendance at a site that is not located in Oxford. Where known, existing collaborations will be outlined on this page. Please read the course information carefully, including the additional information about course fees and costs.
Resources to support your study
As a graduate student, you will have access to the University's wide range of world-class resources including libraries, museums, galleries, digital resources and IT services.
The Bodleian Libraries is the largest library system in the UK. It includes the main Bodleian Library and libraries across Oxford, including major research libraries and faculty, department and institute libraries. Together, the Libraries hold more than 13 million printed items, provide access to e-journals, and contain outstanding special collections including rare books and manuscripts, classical papyri, maps, music, art and printed ephemera.
The University's IT Services is available to all students to support with core university IT systems and tools, as well as many other services and facilities. IT Services also offers a range of IT learning courses for students, to support with learning and research.
You will have access to:
- Experimental facilities, as appropriate to your research
- Extensive IT support from both the CHG and University IT Services
- Library services such as the Radcliffe Science Library and the Cairns Library
The provision of project-specific resources will be agreed with the relevant supervisor during the planning stages for the research project.
The department has been awarded an Athena SWAN Silver award in recognition of the commitment made to promote gender equality through its organisational and cultural practices and its efforts to improve the working environment for both men and women. Students will benefit from the outstanding environment for graduate studies provided within the University of Oxford.
Supervision
The allocation of graduate supervision for this course is the responsibility of the Medical Sciences Doctoral Training Centre and it is not always possible to accommodate the preferences of incoming graduate students to work with a particular member of staff. Under exceptional circumstances a supervisor may be found outside the Medical Sciences Doctoral Training Centre.
The first year will be overseen by an academic mentor who will monitor academic progress and be available to offer advice and support throughout the programme. The final three years of the course will comprise doctoral research under the supervision of two named supervisors and a doctoral committee, who will bring together complementary expertise and experience relevant to the doctoral research. The programme supervisors represent the full spectrum of cutting-edge interdisciplinary research relevant to genomic medicine and statistics across the University with supervisor training and monitoring to ensure the highest quality supervision.
Applicants are advised to visit the course page on the centre's website for further information about supervisors associated with this course (see Further Information and Enquires).
Assessment
All students will be initially admitted to the status of Probationer Research Student (PRS). Within a maximum of six terms as a PRS student you will be expected to apply for transfer of status from Probationer Research Student to DPhil status.
A successful transfer of status from PRS to DPhil status will require the submission of a report on progress to date on research and future plans. Students who are successful at transfer will also be expected to apply for and gain confirmation of DPhil status within ten terms of admission, to show that your work continues to be on track.
Both milestones normally involve an interview with two assessors (other than your supervisor) and therefore provide important experience for the final oral examination.
You will be expected to submit an original thesis of up to 50,000 words within a maximum of four years from the date of admission. To be successfully awarded a DPhil in Genomic Medicine and Statistics you will need to defend your thesis orally (viva voce) in front of two appointed examiners.
Graduate destinations
The interdisciplinary nature of the programme is reflected in the destination of graduates which includes academic research in prestigious laboratories worldwide together with biotech, spin-outs, consulting and working in health care settings.
Changes to this course and your supervision
The University will seek to deliver this course in accordance with the description set out in this course page. However, there may be situations in which it is desirable or necessary for the University to make changes in course provision, either before or after registration. The safety of students, staff and visitors is paramount and major changes to delivery or services may have to be made if a pandemic, epidemic or local health emergency occurs. In addition, in certain circumstances, for example due to visa difficulties or because the health needs of students cannot be met, it may be necessary to make adjustments to course requirements for international study.
Where possible your academic supervisor will not change for the duration of your course. However, it may be necessary to assign a new academic supervisor during the course of study or before registration for reasons which might include illness, sabbatical leave, parental leave or change in employment.
For further information please see our page on changes to courses and the provisions of the student contract regarding changes to courses.
Entry requirements for entry in 2025-26
Proven and potential academic excellence
The requirements described below are specific to this course and apply only in the year of entry that is shown. You can use our interactive tool to help you evaluate whether your application is likely to be competitive.
We know that factors such as socio-economic circumstances and school performance can make it difficult for students to demonstrate their full potential. This course is taking part in an initiative to use contextual data to help us to better understand your achievements in the context of your individual background. For further details, please refer to the information about improving access to graduate study in the How to apply section of this page.
Please be aware that any studentships that are linked to this course may have different or additional requirements and you should read any studentship information carefully before applying. Contextual data may also be used in the assessment of studentships.
Degree-level qualifications
As a minimum, applicants should hold or be predicted to achieve the following UK qualifications or their equivalent:
- a first-class or strong upper second-class undergraduate degree with honours in a relevant biological science or quantitative subject.
However, entrance is very competitive and most successful applicants have a first-class degree or the equivalent.
Substantial professional experience or a graduate qualification may be a substitute for a lower grade at undergraduate level.
For applicants with a degree from the USA, the minimum overall GPA that is normally required to meet the undergraduate-level requirement is 3.5 out of 4.0.
If your degree is not from the UK or another country specified above, visit our International Qualifications page for guidance on the qualifications and grades that would usually be considered to meet the University’s minimum entry requirements.
GRE General Test scores
No Graduate Record Examination (GRE) or GMAT scores are sought.
Other qualifications, evidence of excellence and relevant experience
- Research or working experience in a relevant field may be an advantage.
- Whilst not required, publications demonstrating previous research success in a relevant field is likely to advantage a candidate’s application.
English language proficiency
This course requires proficiency in English at the University's standard level. If your first language is not English, you may need to provide evidence that you meet this requirement. The minimum scores required to meet the University's standard level are detailed in the table below.
| Test | Minimum overall score | Minimum score per component |
|---|---|---|
| IELTS Academic (Institution code: 0713) | 7.0 | 6.5 |
TOEFL iBT, including the 'Home Edition' (Institution code: 0490) | 100 | Listening: 22 Reading: 24 Speaking: 25 Writing: 24 |
| C1 Advanced* | 185 | 176 |
| C2 Proficiency† | 185 | 176 |
*Previously known as the Cambridge Certificate of Advanced English or Cambridge English: Advanced (CAE)
†Previously known as the Cambridge Certificate of Proficiency in English or Cambridge English: Proficiency (CPE)
Your test must have been taken no more than two years before the start date of your course. Our Application Guide provides further information about the English language test requirement.
Declaring extenuating circumstances
If your ability to meet the entry requirements has been affected by the COVID-19 pandemic (eg you were awarded an unclassified/ungraded degree) or any other exceptional personal circumstance (eg other illness or bereavement), please refer to the guidance on extenuating circumstances in the Application Guide for information about how to declare this so that your application can be considered appropriately.
References
You will need to register three referees who can give an informed view of your academic ability and suitability for the course. The How to apply section of this page provides details of the types of reference that are required in support of your application for this course and how these will be assessed.
Supporting documents
You will be required to supply supporting documents with your application. The How to apply section of this page provides details of the supporting documents that are required as part of your application for this course and how these will be assessed.
Performance at interview
Interviews are normally held as part of the admissions process.
Applications are reviewed by a panel of academics associated with the programme. A shortlist of applicants is confirmed, based on assessment of achieved or predicted undergraduate degree grade, academic references, personal statement and CV.
The interview panel will include at least three academics. The interview will be approximately 30 minutes, during which you will be required to give a five-minute presentation on a research project that you have recently carried out as an undergraduate or as part of a research job. The presentation should be made using PowerPoint or a whiteboard.
You will usually have the opportunity to meet current students.
Offer conditions for successful applications
If you receive an offer of a place at Oxford, your offer will outline any conditions that you need to satisfy and any actions you need to take, together with any associated deadlines. These may include academic conditions, such as achieving a specific final grade in your current degree course. These conditions will usually depend on your individual academic circumstances and may vary between applicants. Our 'After you apply' pages provide more information about offers and conditions.
In addition to any academic conditions which are set, you will also be required to meet the following requirements:
Financial Declaration
If you are offered a place, you will be required to complete a Financial Declaration in order to meet your financial condition of admission.
Disclosure of criminal convictions
In accordance with the University’s obligations towards students and staff, we will ask you to declare any relevant, unspent criminal convictions before you can take up a place at Oxford.
Academic Technology Approval Scheme (ATAS)
Some postgraduate research students in science, engineering and technology subjects will need an Academic Technology Approval Scheme (ATAS) certificate prior to applying for a Student visa (under the Student Route). For some courses, the requirement to apply for an ATAS certificate may depend on your research area.
Other factors governing whether places can be offered
The following factors will also govern whether candidates can be offered places:
- the ability of the University to provide the appropriate supervision for your studies, as outlined under the 'Supervision' heading in the About section of this page;
- the ability of the University to provide appropriate support for your studies (eg through the provision of facilities, resources, teaching and/or research opportunities); and
- minimum and maximum limits to the numbers of students who may be admitted to the University's taught and research programmes.
Medical Sciences Doctoral Training Centre
The Medical Sciences Doctoral Training Centre (MSDTC) accommodates the interdisciplinary, cross-departmental DPhil programmes in medical sciences.
Several are structured DPhil programmes, which provide students with the opportunity to undertake two or three 'rotation' projects and relevant course work in their first year of each four-year structured programme. The main doctoral project starts in the second year of such programmes. Other programmes are wholly research based, allowing students to take a research project from the initial proposal through to submitting their thesis. Most of our programmes receive external core-funding, for example from Cancer Research UK and EPSRC.
The MSDTC also accommodates the NIH Oxford-Cambridge Scholars’ Programme, the DPhil in Cancer Science programme funded by CRUK which welcomes applications from clinicians, basic scientists, and medical undergraduates, and the DPhil in Inflammatory and Musculoskeletal Disease which is funded by the Kennedy Trust for Rheumatology Research and is open to medical students wishing to undertake DPhils in the fields of musculoskeletal disease, inflammation and immunology.
Each programme has a distinctive intellectual flavour, designed to nurture independent and creative scientists. Students are supported in their development through:
- supervision and mentoring by world-class academics training in a wide range of research techniques;
- a nurturing research culture with development of student resilience and maintenance of mental health and wellbeing from the start and throughout each programme; and
- being part of a supportive community within individual programmes and across the multi-disciplinary MSDTC.
Funding
We expect that the majority of applicants who are offered a place on this course will also be offered a fully-funded scholarship specific to this course, covering course fees for the duration of their course and a living stipend.
For this course, we recommend that you visit our dedicated funding pages which include details of a range of external funding, loan schemes for postgraduate study. Some scholarships may also be available through our fees, funding and scholarship search tool. You should review the information carefully, including the eligibility criteria and application deadlines, noting that not all funding opportunities are available for postgraduate diploma and postgraduate certificate courses.
Please see the course page on the Graduate School website for further details about funding for this course.
Costs
Annual fees for entry in 2025-26
Fee status | Annual Course fees |
| Home | £10,070 |
| Overseas | £33,370 |
Information about course fees
Course fees are payable each year, for the duration of your fee liability (your fee liability is the length of time for which you are required to pay course fees). For courses lasting longer than one year, please be aware that fees will usually increase annually. For details, please see our guidance on changes to fees and charges.
Course fees cover your teaching as well as other academic services and facilities provided to support your studies. Unless specified in the additional information section below, course fees do not cover your accommodation, residential costs or other living costs. They also don’t cover any additional costs and charges that are outlined in the additional information below.
Continuation charges
Following the period of fee liability, you may also be required to pay a University continuation charge and a college continuation charge. The University and college continuation charges are shown on the Continuation charges page.
Where can I find further information about fees?
The Fees and Funding section of this website provides further information about course fees, including information about fee status and eligibility and your length of fee liability.
Additional information
There are no compulsory elements of this course that entail additional costs beyond fees (or, after fee liability ends, continuation charges) and living costs. However, please note that, depending on your choice of research topic and the research required to complete it, you may incur additional expenses, such as travel expenses, research expenses, and field trips. You will need to meet these additional costs, although you may be able to apply for small grants from your department and/or college to help you cover some of these expenses.
Living costs
In addition to your course fees and any additional course-specific costs, you will need to ensure that you have adequate funds to support your living costs for the duration of your course.
Living costs for full-time study
For the 2025-26 academic year, the range of likely living costs for a single, full-time student is between £1,425 and £2,035 for each month spent in Oxford. We provide the cost per month so you can multiply up by the number of months you expect to live in Oxford. Depending on your circumstances, you may also need to budget for the costs of a student visa and immigration health surcharge and/or living costs for family members or other dependants that you plan to bring with you to Oxford (assuming that dependant visa eligibility criteria are met).
Further information about living costs
The current economic climate and high national rate of inflation make it very hard to estimate potential changes to the cost of living over the next few years. For study in Oxford beyond the 2025-26 academic year, it is suggested that you budget for potential increases in living expenses of around 4% each year – although this rate may vary depending on the national economic situation. For further information, please consult our more detailed information about living costs, which includes a breakdown of likely living costs in Oxford for items such as food, accommodation and study costs.
College preference
Students enrolled on this course will belong to both a department/faculty and a college. Please note that ‘college’ and ‘colleges’ refers to all 43 of the University’s colleges, including those designated as societies and permanent private halls (PPHs).
If you apply for a place on this course you will have the option to express a preference for one of the colleges listed below, or you can ask us to find a college for you. Before deciding, we suggest that you read our brief introduction to the college system at Oxford and our advice about expressing a college preference.
If you are a current Oxford student and you would like to remain at your current Oxford college, you should check whether it is listed below. If it is, you should indicate this preference when you apply. If not, you should contact your college office to ask whether they would be willing to make an exception. Further information about staying at your current college can be found in our Application Guide.
The following colleges accept students on the DPhil in Genomic Medicine and Statistics:
Before you apply
Before you begin an application, we recommend that you consult the Medical Sciences Graduate School's website to identify the most suitable course for your intended area of research.
Our guide to getting started provides general advice on how to prepare for and start your application. You can use our interactive tool to help you evaluate whether your application is likely to be competitive.
If it is important for you to have your application considered under a particular deadline – eg under the December deadline in order to be considered for Oxford scholarships – we recommend that you aim to complete and submit your application at least two weeks in advance. Check the deadlines on this page and the information about deadlines and when to apply in our Application Guide.
Application fee waivers
An application fee of £20 is payable for each application to this course. Application fee waivers are available for the following applicants who meet the eligibility criteria:
- applicants from low-income countries;
- refugees and displaced persons;
- UK applicants from low-income backgrounds; and
- applicants who applied for our Graduate Access Programmes in the past two years and met the eligibility criteria.
You are encouraged to check whether you're eligible for an application fee waiver before you apply.
Readmission for current Oxford graduate taught students
If you're currently studying for an Oxford graduate taught course and apply to this course with no break in your studies, you may be eligible to apply to this course as a readmission applicant. The application fee will be waived for an eligible application of this type. Check whether you're eligible to apply for readmission.
Application fee waivers for eligible associated courses
If you apply to this course and up to two eligible courses during the same application cycle, you can request an application fee waiver so that you only need to pay one application fee. We recommend that you use your application fee waiver to apply only for eligible courses that are closely related in research area to this one.
To be considered eligible for an application fee waiver, each additional course must be:
- doctoral level eg a Doctor of Philosophy (DPhil) or Centre for Doctoral Training (CDT) course; and
- offered by one of the departments in the MPLS Division or one of the departments in the Medical Sciences Division.
If this is the first eligible course that you are applying to, you can request an application fee waiver for an additional course after you have submitted your application for this course. If you have already applied to another course that the meets the eligibility criteria shown above, you should request an application fee waiver before starting an application to this course.
Remember to state clearly in your request which course(s) you intend to apply to. If your request is successful, you will receive an application fee waiver code that is valid for this admission cycle (ie for entry in the 2025-26 academic year). Our Application Guide provides instructions for entering your application fee waiver code.
Do I need to contact anyone before I apply?
You do not need to make contact with the department before you apply but you are encouraged to visit the relevant departmental webpages to read any further information about your chosen course.
Improving access to graduate study
This course is taking part in initiatives to improve the selection procedure for graduate applications, to ensure that all candidates are evaluated fairly.
Socio-economic data (where it has been provided in the application form) will be used as part of an initiative to contextualise applications at the different stages of the selection process.
Completing your application
You should refer to the information below when completing the application form, paying attention to the specific requirements for the supporting documents.
For this course, the application form will include questions that collect information that would usually be included in a CV/résumé. You should not upload a separate document. If a separate CV/résumé is uploaded, it will be removed from your application.
If any document does not meet the specification, including the stipulated word count, your application may be considered incomplete and not assessed by the academic department. Expand each section to show further details.
Proposed field and title of research project
As you do not need to select a project before you apply, please enter 'DPhil in Genomic Medicine and Statistics' under 'Field and title of research project'.
Proposed supervisor
It is not necessary for you to identify a potential supervisor in your application.
Referees:
Three overall, academic preferred
Whilst you must register three referees, the department may start the assessment of your application if two of the three references are submitted by the course deadline and your application is otherwise complete. Please note that you may still be required to ensure your third referee supplies a reference for consideration.
Your references should generally be academic, though professional references are acceptable if they are relevant to the course.
Your references will support intellectual ability, academic achievement, motivation, ability to work in a group.
Official transcript(s)
Your transcripts should give detailed information of the individual grades received in your university-level qualifications to date. You should only upload official documents issued by your institution and any transcript not in English should be accompanied by a certified translation.
More information about the transcript requirement is available in the Application Guide.
Statement of purpose/personal statement:
A maximum of 500 words
You should provide a statement of your research interests, in English, describing how your background and research interests relate to the programme. If possible, please ensure that the word count is clearly displayed on the document.
It will be normal for students’ ideas and goals to change in some ways as they undertake their studies, but your personal statement will enable you to demonstrate your current interests and aspirations.
The statement should focus on academic or research-related achievements and interests rather than personal achievements and interests.
This will be assessed for:
- your reasons for applying;
- evidence of motivation for and understanding of the proposed area of study;
- the ability to present a reasoned case in English;
- capacity for sustained and focused work; and
- understanding of problems in the area and ability to construct and defend an argument.
Start or continue your application
You can start or return to an application using the relevant link below. As you complete the form, please refer to the requirements above and consult our Application Guide for advice.
After you've submitted your application
Your application (including the supporting documents outlined above) will be assessed against the entry requirements detailed on this course page. Whether or not you have secured funding will not be taken into consideration when your application is assessed. You can find out more about our shortlisting and selection process in our detailed guide to what happens next.
Find out how to manage your application after submission, using our Applicant Self-Service tool.