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DPhil in Molecular and Cellular Medicine

About the course

As a DPhil in Molecular and Cellular Medicine student you will spend up to four years (eight years for part-time students) in one of the Kennedy institute of Rheumatology or Botnar Research Centre’s many research groups, working on a research project supervised by the group's principal investigator and your supervisory team. You will take part in the extensive training programme specifically organised for graduate students within the department.

This course is taking part in a continuing pilot programme to improve the assessment procedure for graduate applications, in order to ensure that all candidates are evaluated fairly. For this course, the socio-economic data you provide in the application form will be used to contextualise the shortlisting and decision-making processes where it has been provided.  Please carefully read the instructions concerning submission of your CV/résumé in the How to apply section of this page, as well as the full details about this pilot.

This DPhil programme focuses on molecular and cellular mechanisms of immune function and inflammatory disease. Key research foci include immune mediated inflammatory disease (including Rheumatoid Arthritis and Inflammatory Bowel Disease), mechano-inflammatory disease (including osteoarthritis and tendinopathy), cancer, infection, biophysics, microbiome, metabolism, aging, computational biology, heart disease and tissue healing, using a range of approaches from experimental biology to data sciences.

You will develop your research skills during your first year, including compulsory attendance at the NDORMS fundamentals in biomedical research lectures. During the first term you will develop, in consultation with your supervisor, a training needs plan. Your training will be tailored to your specific project and personal requirements drawing from the vast range of courses available at Oxford and covering specialist scientific methods and transferable skills. Please note that there is no formal taught component of the DPhil in Molecular and Cellular Medicine; however, you will develop your research skills through a range of research training in your first year and attending journal clubs and institute seminar series. During the first term there is compulsory attendance at core lectures on a variety of research techniques and foci in the department including immunology, inflammation, tissue engineering, clinical trial design, epidemiology, rheumatology, orthopaedics and musculoskeletal diseases. During your first year, you will be expected to attend a minimum of three topic-related modules. Attendance on a two-day Data Analysis: Statistics Designing Clinical Research and Biostatistics course is compulsory to assist you with appropriate research design. As a component of your training, you will work with your supervisory team to write a research-specific literature review.

You will be required to attend and present at annual institute student symposia, not only to develop your presentation skills but also to benefit from feedback and interactions from your peers and senior academics, additionally you will have an opportunity to present at internal institute seminar series.

As a member of Medical Sciences Graduate School, you will be entitled to attend various workshops run by the Medical Sciences Skills Training programme. Further academic and pastoral support will be provided for by the Departmental Graduate Studies Team and college advisor.

Applicants are strongly advised to visit the Kennedy and Botnar Institute’s websites (also see Further Information and Enquiries) to help identify the most suitable research topic and related supervisors. Projects are available across a wide range of basic and translational immunology, inflammation, cancer and infection.

Supervision

The allocation of graduate supervision for this course is the responsibility of Medical Sciences and the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) and it is not always possible to accommodate the preferences of incoming graduate students to work with a particular member of staff. Members of the co-supervisory team may come from other departments in the University.

In the case of students who require specific help to adjust to an academic programme or to a new range of skills, the supervisors will work with them to ensure that they have additional support.

All students must have a core supervisory team of at least two co-supervisors. At the beginning of your programme, you will meet with your supervisors regularly to finalise your project and agree on an initial programme of research. Within the first three months, you will complete an analysis of your training needs (TNA) for the duration of your research with your supervisors and submit it as part of your compulsory termly reporting.

Regularity of student/supervisor meetings will be agreed between the student and supervisors directly. Every student should meet their supervisors at least once per month. The Thesis Committee is an important second strand of supervisory support.

Assessment

Your progress will be monitored and assessed regularly via:

  1. completion of a termly report by you and your supervisors through Graduate Supervision Reporting (GSR);
  2. completion of a 5,000-word transfer report and viva before the end of the fourth term (eighth term for part-time students);
  3. completion of a 3,000-word literature review by the end of the seventh term (14th term for part-time students);
  4. confirmation of your status, by viva and presentation, before the end of the ninth term (18th term for part-time students); and
  5. submission of your DPhil thesis (the final stage), which will be assessed by viva at the end of your twelfth term (24th term for part-time students).

Stages 2, 4 and 5 will be assessed by independent senior academics.

Graduate destinations

The department follows alumni to establish the career paths of graduates. Most graduating students go on to pursue research careers in academic institutions or industry. Graduates also pursue careers in management, consulting, teaching, with science funding organisations, charities, and in scientific publishing/editing, some graduates have set up their own businesses.

Changes to this course and your supervision

The University will seek to deliver this course in accordance with the description set out in this course page. However, there may be situations in which it is desirable or necessary for the University to make changes in course provision, either before or after registration. The safety of students, staff and visitors is paramount and major changes to delivery or services may have to be made in circumstances of a pandemic (including Covid-19), epidemic or local health emergency. In addition, in certain circumstances, for example due to visa difficulties or because the health needs of students cannot be met, it may be necessary to make adjustments to course requirements for international study.

Where possible your academic supervisor will not change for the duration of your course. However, it may be necessary to assign a new academic supervisor during the course of study or before registration for reasons which might include illness, sabbatical leave, parental leave or change in employment.

For further information please see our page on changes to courses and the provisions of the student contract regarding changes to courses.

Other courses you may wish to consider

Applicants are strongly advised to visit the Medical Sciences Graduate School website to help them identify the most suitable course and supervisors.

If you're thinking about applying for this course, you may also wish to consider the courses listed below. These courses may have been suggested due to their similarity with this course, or because they are offered by the same department or faculty.

All graduate courses offered by the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences

Entry requirements for entry in 2022-23

Proven and potential academic excellence

Degree-level qualifications

As a minimum, applicants should hold or be predicted to achieve the equivalent of the following UK qualifications:

  • a first-class or strong upper second-class undergraduate degree with honours

You do not need to have a previous master's degree to be considered for this DPhil.

In exceptional circumstances, if the above criteria are not met, an applicant could be considered if they have substantial professional experience in a related field.

For applicants with a degree from the USA, the minimum GPA sought is 3.5 out of 4.0.

If your degree is not from the UK or another country specified above, visit our International Qualifications page for guidance on the qualifications and grades that would usually be considered to meet the University’s minimum entry requirements.

GRE General Test scores

No Graduate Record Examination (GRE) or GMAT scores are sought.

Other qualifications, evidence of excellence and relevant experience

  • Although recent publications are beneficial, we recognise that not all applicants will have had the opportunity to undertake lab based research leading to publications due to circumstances beyond their control or are involved in data science / ‘team science’ projects thus we are looking for candidates to show evidence of motivation that might result from a range of different activities including non-lab based research.
  • Research or working experience in any field may be an advantage.
  • It would be expected that applicants will be familiar with the recent published work of their proposed supervisors.
  • For clinical applicants evidence of your NHS or HSE trust support will be required.

Extenuating circumstances

If your ability to meet the entry requirements has been affected by the COVID-19 pandemic (eg you were awarded an unclassified/ungraded degree) or any other exceptional personal circumstance (eg other illness or bereavement), please refer to the guidance on extenuating circumstances in the Application Guide for information about how to declare this so that your application can be considered appropriately.

English language requirement

This course requires proficiency in English at the University's standard level. If your first language is not English, you may need to provide evidence that you meet this requirement. The minimum scores required to meet the University's standard level are detailed in the table below.

Minimum scores required to meet the University's standard level requirement
TestMinimum overall scoreMinimum score per component
IELTS Academic (Institution code: 0713) 7.06.5

TOEFL iBT, including the 'Home Edition'

(Institution code: 0490)

100Listening: 22
Reading: 24
Speaking: 25
Writing: 24
C1 Advanced*185176
C2 Proficiency185176

*Previously known as the Cambridge Certificate of Advanced English or Cambridge English: Advanced (CAE)
Previously known as the Cambridge Certificate of Proficiency in English or Cambridge English: Proficiency (CPE)

Your test must have been taken no more than two years before the start date of your course. Our Application Guide provides further information about the English language test requirement.

Supporting documents 

You will be required to supply supporting documents with your application, including references and an official transcript. See 'How to apply' for instructions on the documents you will need and how these will be assessed.

Performance at interview

Interviews are normally held as part of the admissions process.  

All shortlisted candidates will be interviewed in person or by video-conference (depending on the applicant's native country). The interview will be conducted by senior academics and it will last ~30 mins. Those shortlisted for interviews will be notified 7 to 14 days prior to the interview date.

The shortlisted applicants will be required to give a short presentation on their previous research.

Supervision

Any offer of a place is dependent on the University’s ability to provide the appropriate supervision for your chosen area of work. Please refer to the ‘About’ section of this page for more information about the provision of supervision for this course.

How your application is assessed

Your application will be assessed purely on academic merit and potential, according to the published entry requirements for the course. The After you apply section of this website provides further information about the academic assessment of your application, including the potential outcomes. Please note that any offer of a place may be subject to academic conditions, such as achieving a specific final grade in your current degree course. These conditions may vary depending upon your individual academic circumstances.

Students are considered for shortlisting and selected for admission without regard to gender, marital or civil partnership status, disability, race, nationality, ethnic origin, religion or belief, sexual orientation, age or social background. Whether you have secured funding will not be taken into consideration when your application is assessed.

Admissions panels and assessors

All recommendations to admit a student involve the judgement of at least two members of the academic staff with relevant experience and expertise, and must also be approved by the Director of Graduate Studies or Admissions Committee (or equivalent within the department).

Admissions panels or committees will always include at least one member of academic staff who has undertaken appropriate training.

After an offer is made

If you receive an offer of a place at Oxford, your offer letter will give full details of your offer and any academic conditions, such as achieving a specific final grade in your current degree course.  In addition to any academic conditions which are set, you will be required to meet the following requirements:

Financial Declaration

If you are offered a place, you will be required to complete a Financial Declaration in order to meet your financial condition of admission.

Disclosure of criminal convictions

In accordance with the University’s obligations towards students and staff, we will ask you to declare any relevant, unspent criminal convictions before you can take up a place at Oxford.

Academic Technology Approval Scheme (ATAS)

Some postgraduate research students in science, engineering and technology subjects will need an Academic Technology Approval Scheme (ATAS) certificate prior to applying for a Tier 4 visa. Further information can be found on our Tier 4 (General) Student visa page. For some courses, the requirement to apply for an ATAS certificate may depend on your research area.

Resources

The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is a large multi- disciplinary department including the Kennedy Institute and the Botnar and Kadoorie Research Centres with a broad range of sciences related to medicine. Research spans the translational research spectrum, from basic biological research through to clinical and epidemiological research.

The NDORMS is committed to training the next generation of scientists in biological and clinical sciences and with over 400 people, approximately 100 postgraduate research students and a grant portfolio in excess of £150 million.

NDORMS has state-of-the-art research facilities across the spectrum of our research expertise.

There is student representation within the various departmental committees, providing student-led support as well as representing students’ interests on departmental decision making.

You will have access to a wide range of resources within the institute, department and University, including the following facilities:

IT support

You will have access to University IT services and Medical Sciences Division IT support. You will be allocated unique single-sign-on (SSO) credentials which will allow you to access numerous resources such as information on local seminars (Oxford Talk), other departmental and University information, the divisional skills training portal, significant information on the University student gateway, career courses and libraries online.

Libraries

You will have access to local libraries: the Bodleian Library, the Cairns Library based in the John Radcliffe Hospital and musculoskeletal-related topics at the Girdlestone Library, located at the Nuffield Orthopaedic Centre and Knowledge Centre on the Old Road Campus. Furthermore, through the central University library services, you will have online access to a wide range of articles and publications.

Study and experimental space

Workspace will be related to and dependent on your individual circumstances. If undertaking experimental 'wet' lab work, you will be provided with bench space in a relevant laboratory. If undertaking data analysis and computer-based research, you will be allocated an office space that may be shared.

Lectures and seminars

You will be notified by regular emails about seminar schedules within the department and you are encouraged to visit the Oxford Talk website to access other departments' and divisions' seminars and lectures.

NDORMS Student Committee

Currently there are around 100 DPhil and MSc research students. There is an active student committee which organises regular social events, a Christmas gathering with a band and a picnic in the park during the summer. At least two students are represented at the department’s Graduate Studies Committee, the Athena SWAN Committee and the University's Graduate Joint Consultative Committee to express students' opinions, concerns and views.

Funding

The University expects to be able to offer around 1,000 full or partial graduate scholarships across the collegiate University in 2022-23. You will be automatically considered for the majority of Oxford scholarships, if you fulfil the eligibility criteria and submit your graduate application by the relevant December or January deadline. Most scholarships are awarded on the basis of academic merit and/or potential. 

For further details about searching for funding as a graduate student visit our dedicated Funding pages, which contain information about how to apply for Oxford scholarships requiring an additional application, details of external funding, loan schemes and other funding sources. Please ensure that you visit individual college websites for details of college-specific funding opportunities using the links provided on our college pages.

Further information about funding opportunities for this course can be found on the department's website. All Kennedy Trust Prize Studentships (KTPS) projects are fully funded.

Costs

Full-time study

Fee status

Annual Course fees

Home£8,620
Overseas£28,560

Further details about fee status eligibility can be found on the fee status webpage.

Part-time study

Fee status

Annual Course fees

Home£4,310
Overseas£14,280

Further details about fee status eligibility can be found on the fee status webpage.

Course fees are payable each year, for the duration of your fee liability (your fee liability is the length of time for which you are required to pay course fees). For courses lasting longer than one year, please be aware that fees will usually increase annually. For details, please see our guidance on changes to fees and charges.

Course fees cover your teaching as well as other academic services and facilities provided to support your studies. Unless specified in the additional information section below, course fees do not cover your accommodation, residential costs or other living costs. They also don’t cover any additional costs and charges that are outlined in the additional information below.

Following the period of fee liability, you may also be required to pay a University continuation charge and a college continuation charge. The University and college continuation charges are shown on the Continuation charges page.

For more information about course fees and fee liability, please see the Fees section of this website. EU applicants should refer to our detailed fee status information and the Oxford and the EU webpage for details of the implications of the UK’s exit from the EU.

Additional information

Full-time study

There are no compulsory elements of this course that entail additional costs beyond fees (or, after fee liability ends, continuation charges) and living costs. However, please note that, depending on your choice of research topic and the research required to complete it, you may incur additional expenses, such as travel expenses, research expenses, and field trips. You will need to meet these additional costs, although you may be able to apply for small grants from your department and/or college to help you cover some of these expenses.

Part-time study

Please note that you are required to attend in Oxford for a minimum of 30 days each year, and you may incur additional travel and accommodation expenses for this. Also, depending on your choice of research topic and the research required to complete it, you may incur further additional expenses, such as travel expenses, research expenses, and field trips. You will need to meet these additional costs, although you may be able to apply for small grants from your department and/or college to help you cover some of these expenses.

Living costs

In addition to your course fees, you will need to ensure that you have adequate funds to support your living costs for the duration of your course.

For the 2022-23 academic year, the range of likely living costs for full-time study is between c. £1,215 and £1,755 for each month spent in Oxford. Full information, including a breakdown of likely living costs in Oxford for items such as food, accommodation and study costs, is available on our living costs page. When planning your finances for any future years of study in Oxford beyond 2022-23, you should allow for an estimated increase in living expenses of 3% each year.

If you are studying part-time your living costs may vary depending on your personal circumstances but you must still ensure that you will have sufficient funding to meet these costs for the duration of your course.

College preference

All graduate students at Oxford belong to a department or faculty and a college or hall (except those taking non-matriculated courses). If you apply for a place on this course you will have the option to express a preference for one of the colleges listed below, or you can ask us to find a college for you. The Colleges section of this website provides information about the college system at Oxford, as well as factors you may wish to consider when deciding whether to express a college preference. Please note that ‘college’ and ‘colleges’ refers to all 45 of the University’s colleges, including those designated as Permanent Private Halls (PPHs). 

For some courses, the department or faculty may have provided some additional advice below to help you to decide. Whatever you decide, it won’t affect how the academic department assesses your application and whether they decide to make you an offer. If your department makes you an offer of a place, you’re guaranteed a place at one of our colleges. 

The Molecular and Cellular Medicine DPhil suggests applicants consider selecting from one of the following four colleges with which the program has a strong relationship: Reuben College, Wolfson College, St Edmund Hall, or St Cross College. You are free to list any other college that accepts Molecular and Cellular Medicine on your application form, but strongly encourage consideration one of the four listed colleges.

How to apply

Please read all the instructions carefully before starting your application. You should pay particular attention to the instructions concerning the submission of your CV/résumé below.

You should make contact with the academic member of staff with whom you wish to undertake research in order to ascertain the suitability of the project to your experience. Details of potential supervisors can be found on the Kennedy Institute and Botnar Research Centre websites. Whether you have contacted a prospective supervisor will be taken into account at the shortlisting and interview stage.

The set of documents you should send with your application to this course comprises the following:

Official transcript(s)

Your transcripts should give detailed information of the individual grades received in your university-level qualifications to date. You should only upload official documents issued by your institution and any transcript not in English should be accompanied by a certified translation.

More information about the transcript requirement is available in the Application Guide.

CV/résumé
Full instructions and link to standard CV creation form

A CV/résumé is compulsory for all applications. You will need to upload a standardised CV to the graduate application form as part of your application. This standardised CV should be generated using the online form that requests certain information that you will likely have included on your CV. Once you have completed the form, you will have 15 minutes to download your CV as a PDF document. 

This PDF document will be in the same format for all applicants and you should not modify the document before you upload it, or submit your CV in a different format. 

Full instructions and a link to the standard CV creation form are provided on the Medical Sciences Division website. The instructions page contains links to example clinical and non-clinical CVs, with details of what to include and suggested answer formats.

If you require help or advice while generating your CV using the online form, please contact the Medical Sciences Graduate School for assistance (graduate.school@medsci.ox.ac.uk).

You can find more information about the standard CV form on our page that provides details of the continuing pilot programme to improve the assessment procedure for graduate applications.

Statement of purpose/personal statement:
A maximum of 500 words, plus an optional extended statement of a maximum of 1,000 words

Statement of purpose/personal statement

All applicants need to submit a statement of purpose/personal statement.

You should provide a statement of your research interests, in English, describing how your background and research interests relate to the programme. If possible, please ensure that the word count is clearly displayed on the document.

The statement should focus on academic or research-related achievements and interests rather than personal achievements and interests.

This will be assessed for:

  • your reasons for applying;
  • evidence of motivation for and understanding of the proposed area of study;
  • the ability to present a reasoned case in English;
  • capacity for sustained and focused work; and
  • understanding of problems in the area and ability to construct and defend an argument.

It will be normal for students’ ideas and goals to change in some ways as they undertake their DPhil, but your personal statement will enable you to demonstrate your current interests and aspirations.

Extended statement (optional)

You may also submit an optional extended statement in addition to the mandatory statement of purpose/personal statement. The extended statement should be written in English and be a maximum of 1,000 words.

If you decide to submit an extended statement in addition to the mandatory statement of purpose/personal statement, both statements should be uploaded in a single document with clear subheadings. 

The extended statement can be used to provide further detailed evidence of your motivation, relevant skills and/or experiences that enable further insight into your potential as a DPhil student. You might want to highlight in more detail your research outputs or research skills (wet lab or data analysis) and how that links to your project choice. If you have undertaken a team-based research project, please detail your role in that project. If you have had to overcome any personal or research project adversities, please highlight these in this extended statement.

References/letters of recommendation:
Three overall, of which at least two must be academic

Whilst you must register three referees, the department may start the assessment of your application if two of the three references are submitted by the course deadline and your application is otherwise complete. Please note that you may still be required to ensure your third referee supplies a reference for consideration.

One professional reference is acceptable, though your other references should be academic and should comment specifically on your academic ability.

Your references should support your intellectual ability, academic achievement, motivation and ability to work independently.

Start or continue an application

Step 1: Read our guide to getting started, which explains how to prepare for and start an application.

Step 2: Check that you meet the Entry requirements and read the How to apply information on this page.

Step 3: Check the deadlines on this page and the deadline information in our Application Guide. Plan your time to submit your application well in advance - we recommend two or three weeks earlier.

Step 4: Check if you're eligible for an application fee waiver. Application fee waivers are available for:

Step 5: Start your application using the relevant link below. As you complete the form, consult our Application Guide for advice at each stage. You'll find the answers to most common queries in our FAQs.

Application GuideApply - Full timeApply - Part time

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