DPhil in Molecular and Cellular Medicine | University of Oxford
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DPhil in Molecular and Cellular Medicine

About the course

As a DPhil in Molecular and Cellular Medicine student you will spend up to four years (eight years for part-time students) in one of the department's many research groups, working on a project supervised by the group's principal investigator. You will take part in the extensive training programme specifically organised for graduate students within the department.

The NDORMS department aims to discover the causes of musculoskeletal and inflammatory conditions to deliver excellent and innovative care that improves people’s quality of life. The department consists of three different centres/institutes, the Botnar Research Centre, the Kennedy Institute of Rheumatology and the Kadoorie Centre containing a number of world leading research units.  There are two separate graduate programs one for the Botnar and Kadoorie institutes and one for the Kennedy Institute of Rheumatology each with different entry requirements and application procedures.

You will develop your research skills through a range of research training in your first year, including compulsory attendance at our fundamentals in biomedical research lectures in your first week. During the first term you will develop, in consultation with your supervisor, a clear study design for your project.

Your training will be tailored to your particular needs, drawing from the vast range of training available at Oxford and covering specialist scientific methods, techniques and transferable skills. Please note that there is no formal taught component of the DPhil in Molecular and Cellular Medicine; however, you will develop your research skills through a range of research training in your first year. This will include compulsory attendance to core subjects with lectures on a variety of topics such as an introduction to “immunology, inflammation, tissue engineering, clinical trial design, epidemiology, rheumatology, orthopaedics and musculoskeletal disease”.

During your first year, you will be expected to attend a minimum of three topic-related modules. Attendance on a two-day Data Analysis: Statistics Designing Clinical Research and Biostatistics course is compulsory to assist you with appropriate research design. You are also encouraged to work with your supervisor(s) on your research-specific literature review and to develop a study design for your thesis within the first term (two terms for part-time students) of your research training.

You will be required to attend and present at postgraduate seminars, not only to develop your presentation skills but also to benefit from the feedback, support and interaction from your University peers and senior academics.

As a member of Medical Sciences Graduate School, you will be entitled to attend various workshops run by the Medical Sciences Skills Training programme. Further academic and pastoral support will be provided for by the Departmental Graduate Studies Team which consist of the Director of Graduate Studies as well as the departmental Graduate Studies Officer and Assistant. Further support is available from your college advisor.

Applicants are strongly advised to visit the department's website (see Further Information and Enquiries) to help them identify the most suitable research topic and related supervisors. Projects are available in both basic and translational science covering a variety of areas related to musculoskeletal and chronic inflammatory conditions.

Supervision

The allocation of graduate supervision for this course is the responsibility of Medical Sciences and the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) and it is not always possible to accommodate the preferences of incoming graduate students to work with a particular member of staff. Under exceptional circumstances a supervisor may be found outside Medical Sciences and NDORMS.

In the case of students who require specific help to adjust to an academic programme or to a new range of skills, the supervisor will work with them to ensure that they have additional support.

All students must have at least two supervisors (usually a Primary Supervisor and a co-supervisor). At the beginning of your programme, you will meet with your supervisors regularly to finalise your project and agree on an initial programme of research. Within the first three months, you will complete an analysis of your training needs for the duration of your research (TNA) with your supervisor and submit it as part of your compulsory termly reporting.

Regularity of student/supervisor meetings will be agreed between the student and supervisors directly. Every student should meet their supervisors at least once per term; though it is expected that meetings will occur more regularly. A Thesis Committee is a compulsory second strand of supervisory support in the Kennedy Institute.

Assessment

Your progress will be monitored and assessed regularly via:

  1. completion of a termly report by you and your supervisors through Graduate Supervision Reporting (GSR);
  2. completion of a 5,000-word transfer report and viva before the end of the fourth term (eight term for part-time students);
  3. completion of a 3,000-word literature review by the end of the seventh term (students based in the Kennedy Institute only – 14th term for part-time students);
  4. confirmation of your status, by viva and presentation, before the end of the ninth term (18th term for part-time students); and
  5. submission of your DPhil thesis (the final stage), which will be assessed by viva at the end of your twelfth term (24th term for part-time students).

Stages 2, 4 and 5 will be assessed by independent senior academics.

Graduate destinations

The department follows alumni to establish the career paths of graduates. The majority of graduating students go on to pursue research careers in academic institutions or industry. Graduates also pursue careers in management, consulting, teaching, with science funding organisations, charities, and in scientific publishing/editing. A number of graduates have set up their own businesses (eg in editing).

Changes to this course and your supervision

The University will seek to deliver this course in accordance with the description set out in this course page. However, there may be situations in which it is desirable or necessary for the University to make changes in course provision, either before or after registration. The safety of students, staff and visitors is paramount and major changes to delivery or services may have to be made in circumstances of a pandemic (including Covid-19), epidemic or local health emergency. In addition, in certain circumstances, for example due to visa difficulties or because the health needs of students cannot be met, it may be necessary to make adjustments to course requirements for international study.

Where possible your academic supervisor will not change for the duration of your course. However, it may be necessary to assign a new academic supervisor during the course of study or before registration for reasons which might include illness, sabbatical leave, parental leave or change in employment.

For further information please see our page on changes to courses and the provisions of the student contract regarding changes to courses.

Other courses you may wish to consider

Applicants are strongly advised to visit the Medical Sciences Graduate School website to help them identify the most suitable course and supervisors.

If you're thinking about applying for this course, you may also wish to consider the courses listed below. These courses may have been suggested due to their similarity with this course, or because they are offered by the same department or faculty.

All graduate courses offered by the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences

Entry requirements for entry in 2021-22

Proven and potential academic excellence

Degree-level qualifications

As a minimum, applicants should hold or be predicted to achieve the equivalent of the following UK qualifications:

  • a first-class or strong upper second-class undergraduate degree with honours in biological sciences and/or related topics.

The department also considers applicants from medically qualified individuals. In special circumstances, applications from other medically related subjects (eg nurses, and/or allied health professionals) will be considered for the DPhil. If you believe you fall into this category, please contact the Graduate Studies Officer.

You do not need to have a previous master's degree to be considered for this DPhil.

In exceptional circumstances, an applicant could be considered if they have substantial professional experience in a related field.

For applicants with a degree from the USA, the minimum GPA sought is 3.5 out of 4.0.

If your degree is not from the UK or another country specified above, visit our International Qualifications page for guidance on the qualifications and grades that would usually be considered to meet the University’s minimum entry requirements.

GRE General Test scores

No Graduate Record Examination (GRE) or GMAT scores are sought.

Other qualifications, evidence of excellence and relevant experience

You will be applying to undertake research in either the Botnar Research Centre or the Kennedy Institute of Rheumatology. Due to differences in the entry requirements (outlined below), you are advised to check the location where your proposed research will be based with your potential supervisor (see How to apply for further details).

Botnar Research Centre

  • Although it is not essential, preference will be given to applicants who have had recent publications and/or awards from various funding bodies.
  • Previous publications are not a requirement; however, they would be advantageous to your application.
  • Research or working experience in any field may be an advantage. For clinical applicants, evidence of your employer's support will be required.
  • It would be expected that graduate applicants would be familiar with the recent published work of their proposed supervisor.

Kennedy Institute of Rheumatology

  • Although recent publications are beneficial, we recognise that not all applicants will have had the opportunity to undertake lab based research leading to publications due circumstances beyond their control, thus we are looking for candidates to show evidence of motivation that might result from a range of different activities including non-lab based research
  • Research or working experience in any field may be an advantage
  • It would be expected that applicants will be familiar with the recent published work of their proposed supervisors
  • For clinical applicants for KTPS Clinical DPhil program evidence of your NHS trust support will be required

Extenuating circumstances

If your ability to meet the entry requirements has been affected by the COVID-19 pandemic (eg you were awarded an unclassified/ungraded degree) or any other exceptional personal circumstance (eg other illness or bereavement), please refer to the guidance on extenuating circumstances in the Application Guide for information about how to declare this so that your application can be considered appropriately.

English language requirement

This course requires proficiency in English at the University's standard level. If your first language is not English, you may need to provide evidence that you meet this requirement. The minimum scores required to meet the University's standard level are detailed in the table below.

Minimum scores required to meet the University's standard level requirement
TestMinimum overall scoreMinimum score per component
IELTS Academic (Institution code: 0713) 7.06.5
TOEFL iBT (Institution code: 0490)100Listening: 22
Reading: 24
Speaking: 25
Writing: 24
C1 Advanced*185176
C2 Proficiency185176

*Previously known as the Cambridge Certificate of Advanced English or Cambridge English: Advanced (CAE)
Previously known as the Cambridge Certificate of Proficiency in English or Cambridge English: Proficiency (CPE)

Your test must have been taken no more than two years before the start date of your course. Our Application Guide provides further information about the English language test requirement.

Supporting documents 

You will be required to supply supporting documents with your application, including references and an official transcript. See 'How to apply' for instructions on the documents you will need and how these will be assessed.

Performance at interview

Interviews are normally held as part of the admissions process.  

All shortlisted candidates will be interviewed in person or by Skype or video-conference (depending on the applicant's native country). The interview will be conducted by up to five senior academics and it will last a maximum of 45 minutes. Those shortlisted for interviews will be notified 7 to 14 days prior to the interview date. 

The shortlisted applicants will be required to give a 10-15 minute presentation on their previous research or that proposed to be undertaken for the DPhil.

Supervision

Any offer of a place is dependent on the University’s ability to provide the appropriate supervision for your chosen area of work. Please refer to the ‘About’ section of this page for more information about the provision of supervision for this course.

How your application is assessed

Your application will be assessed purely on academic merit and potential, according to the published entry requirements for the course. Students are selected for admission without regard to gender, marital or civil partnership status, disability, race, nationality, ethnic origin, religion or belief, sexual orientation, age or social background. Whether you have secured funding will not be taken into consideration when your application is assessed.

Admissions panels and assessors

All recommendations to admit a student involve the judgement of at least two members of the academic staff with relevant experience and expertise, and must also be approved by the Director of Graduate Studies or Admissions Committee (or equivalent within the department).

Admissions panels or committees will always include at least one member of academic staff who has undertaken appropriate training.

After an offer is made

If you receive an offer of a place at Oxford, you will be required to meet the following requirements: 

Financial Declaration

If you are offered a place, you will be required to complete a Financial Declaration in order to meet your financial condition of admission.

Disclosure of criminal convictions

In accordance with the University’s obligations towards students and staff, we will ask you to declare any relevant, unspent criminal convictions before you can take up a place at Oxford.

Academic Technology Approval Scheme (ATAS)

Some postgraduate research students in science, engineering and technology subjects will need an Academic Technology Approval Scheme (ATAS) certificate prior to applying for a Tier 4 visa. Further information can be found on our Tier 4 (General) Student visa page. For some courses, the requirement to apply for an ATAS certificate may depend on your research area.

Resources

The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) is a large multi-disciplinary department with a broad range of sciences related to medicine. Research spans the translational research spectrum, from basic biological research through to clinical and epidemiological research.

The NDORMS is committed to training the next generation of scientists in biological and clinical sciences and has a large number of staff (over 400 people), approximately 100 postgraduate research students and a grant portfolio of £147 million.

NDORMS has state-of-the-art research facilities across the spectrum of our research expertise.

There is student representation within the various departmental committees, providing student-led support as well as representing students’ interests on departmental decision making.

You will have access to a wide range of resources within the department and University, including the following facilities:

IT support

You will have access to University IT services and Medical Sciences Division IT support. You will be allocated unique single-sign-on (SSO) credentials which will allow you to access numerous resources such as information on local seminars (Oxford Talk), other departmental and University information, the divisional skills training portal, significant information on the University student gateway, career courses and libraries online.

Libraries

You will have access to local libraries: the Cairns Library based in the John Radcliffe Hospital and musculoskeletal-related topics at the Girdlestone Library located at the Nuffield Orthopaedic Centre. Furthermore, through the central University library services, you will have access to a wide range of articles and publications.

Study and experimental space

Workspace will be related to and dependent on your individual circumstances. If undertaking experimental 'wet' lab work, you will be provided with bench space in a relevant laboratory. If undertaking data analysis and computer-based research, you will be allocated an office space that may be shared.

Lectures and seminars

You will be notified by regular emails about seminar schedules within the department and you are encouraged to visit the Oxford Talk website to access other departments' and divisions' seminars and lectures.

NDORMS Student Committee

Currently there are around 100 DPhil and MSc research students. There is an active student committee which organises regular social events, a Christmas gathering with a band and a picnic in the park during the summer. At least two students are represented at the department’s Graduate Studies Committee, the Athena SWAN Committee and the University's Graduate Joint Consultative Committee to express students' opinions, concerns and views.

Funding

The University expects to be able to offer up to 1,000 full or partial graduate scholarships across the collegiate University in 2021-22. You will be automatically considered for the majority of Oxford scholarships, if you fulfil the eligibility criteria and submit your graduate application by the relevant January deadline. Most scholarships are awarded on the basis of academic merit and/or potential. 

For further details about searching for funding as a graduate student visit our dedicated Funding pages, which contain information about how to apply for Oxford scholarships requiring an additional application, details of external funding, loan schemes and other funding sources. Please ensure that you visit individual college websites for details of college-specific funding opportunities using the links provided on our college pages.

Further information about funding opportunities for this course can be found on the department's website.

Costs

Full-time study

Fee status

Annual Course fees

Home (UK, Republic of Ireland,
Channel Islands & Isle of Man)
£8,290
Overseas (including EU)£27,460

Part-time study

This information is currently unavailable: please check back again soon

Course fees are payable each year, for the duration of your fee liability (your fee liability is the length of time for which you are required to pay course fees). For courses lasting longer than one year, please be aware that fees will usually increase annually. For details, please see our guidance on likely increases to fees and charges.

Course fees cover your teaching as well as other academic services and facilities provided to support your studies. Unless specified in the additional information section below, course fees do not cover your accommodation, residential costs or other living costs. They also don’t cover any additional costs and charges that are outlined in the additional information below.

Following the period of fee liability, you may also be required to pay a University continuation charge and a college continuation charge. The University and college continuation charges are shown on the Continuation charges page.

For more information about course fees and fee liability, please see the Fees section of this website. EU applicants should refer to our detailed fee status information and the Oxford and the EU webpage for details of the implications of the UK’s exit from the EU.

Additional information

Full-time study

There are no compulsory elements of this course that entail additional costs beyond fees (or, after fee liability ends, continuation charges) and living costs. However, please note that, depending on your choice of research topic and the research required to complete it, you may incur additional expenses, such as travel expenses, research expenses, and field trips. You will need to meet these additional costs, although you may be able to apply for small grants from your department and/or college to help you cover some of these expenses.

Part-time study

Please note that you are required to attend in Oxford for a minimum of 30 days each year, and you may incur additional travel and accommodation expenses for this. Also, depending on your choice of research topic and the research required to complete it, you may incur further additional expenses, such as travel expenses, research expenses, and field trips. You will need to meet these additional costs, although you may be able to apply for small grants from your department and/or college to help you cover some of these expenses.

Living costs

In addition to your course fees, you will need to ensure that you have adequate funds to support your living costs for the duration of your course.

For the 2021-22 academic year, the range of likely living costs for full-time study is between c. £1,175 and £1,710 for each month spent in Oxford. Full information, including a breakdown of likely living costs in Oxford for items such as food, accommodation and study costs, is available on our living costs page. When planning your finances for any future years of study in Oxford beyond 2021-22, you should allow for an estimated increase in living expenses of 3% each year.

If you are studying part-time your living costs may vary depending on your personal circumstances but you must still ensure that you will have sufficient funding to meet these costs for the duration of your course.

College preference

All graduate students at Oxford belong to a department or faculty and a college or hall (except those taking non-matriculated courses). If you apply for a place on this course you will have the option to express a preference for one of the colleges listed below, or you can ask us to find a college for you. The Colleges section of this website provides information about the college system at Oxford, as well as factors you may wish to consider when deciding whether to express a college preference. Please note that ‘college’ and ‘colleges’ refers to all 45 of the University’s colleges, including those designated as Permanent Private Halls (PPHs). 

For some courses, the department or faculty may have provided some additional advice below to help you to decide. Whatever you decide, it won’t affect how the academic department assesses your application and whether they decide to make you an offer. If your department makes you an offer of a place, you’re guaranteed a place at one of our colleges. 

The Kennedy Institute suggests applicants consider selecting from one of the following four colleges with which the Kennedy graduate program has a strong relationship: Reuben College, Wolfson College, St Edmund Hall, or St Cross College. You are free to list any college on your application form, but the institute strongly encourages you to consider one of the four listed colleges.

How to apply

You should make contact with the academic member of staff with whom you wish to undertake research in order to ascertain the suitability of the project to your experience. Details of potential supervisors can be found on the NDORMS or Kennedy Institute websites. You will be applying to undertake research in either the Botnar Research Centre or the Kennedy Institute of Rheumatology. As there are differences in the entry requirements and supporting materials required in your application (which are outlined below), you are advised to check the location where your proposed research will be based with your potential supervisor. Whether you have contacted a prospective supervisor will be taken into account at the shortlisting and interview stage.

The set of documents you should send with your application to this course comprises the following:

Official transcript(s)

Your transcripts should give detailed information of the individual grades received in your university-level qualifications to date. You should only upload official documents issued by your institution and any transcript not in English should be accompanied by a certified translation.

More information about the transcript requirement is available in the Application Guide.

CV/résumé

A CV/résumé is compulsory for all applications. Most applicants choose to submit a document of one to two pages highlighting their academic achievements and any relevant professional experience.

Research proposal and personal statement/covering letter:
Proposal of a maximum of 500 words, statement of a maximum of 500 words

Only required for applications to the Botnar Research Centre.

You should submit a detailed outline of your proposed research, written in English. You are also encouraged to include a personal statement and/or a covering letter with your application, as a combined document with your research proposal. The overall word count should include any bibliography.

If possible, please ensure that the word count is clearly displayed on the document.

The research proposal should include details of the background/rationale of the research, hypotheses, methodology. It should explain the originality/novelty of the work and outline how a commitment to complete it within 12 academic terms can be achieved.

The statement or covering letter should address your motivations for applying to the course and your relevant skills and experience.

The personal statement/covering letter should include, and will be assessed for:

  • your reasons for applying
  • motivation for the area of study
  • capacity for sustained and intense work
  • reasoning ability
  • ability to absorb new ideas, often presented abstractly, at a rapid pace.

It will be normal for your ideas subsequently to change in some ways as you investigate the evidence and develop your project. You should nevertheless make the best effort you can to demonstrate the extent of your research question, sources and method at this moment.

Personal statement:
A maximum of 1,500 words

Only required for applications for the Kennedy Trust Prize studentship or an advertised studentship in the Kennedy Institute. 

If you are applying to a Kennedy Trust Prize studentship or other advertised studentship in the Kennedy Institute, you need to submit a personal statement providing evidence of motivation and relevant experiences for applying for the DPhil course and your relevant skills and experience.

If possible, please ensure that the word count is clearly displayed on the document.

The personal statement might include:

  • Your reasons for applying for a DPhil in the Kennedy Institute
  • Motivation for the choice of supervisor(s) and project(s)
  • How you have responded to any adversity
  • Evidence of commitment and/or relevant research experiences
  • Reasoning ability
  • Ability to absorb new ideas
  • Evidence of oral and written presentation skills

You should not submit a research proposal when applying to the Kennedy Institute.

References/letters of recommendation:
Three overall, of which at least two must be academic

Whilst you must register three referees, the department may start the assessment of your application if two of the three references are submitted by the course deadline and your application is otherwise complete. Please note that you may still be required to ensure your third referee supplies a reference for consideration.

One professional reference is acceptable, though your other references should be academic and should comment specifically on your academic ability.

Your references should support intellectual ability, academic achievement, motivation and ability to work independently.

Start or continue an application

Step 1: Read our guide to getting started, which explains how to prepare for and start an application.

Step 2: Check that you meet the Entry requirements and read the How to apply information on this page.

Step 3: Check the deadlines on this page and plan your time to submit your application well in advance.

Step 4: Our Application Guide will help you complete the form. It contains links to FAQs and further help.

Step 5: Submit your application as soon as possible (you can read more information about our deadlines).

Application GuideApply - Full timeApply - Part time

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