Research

Oxford University is world-famous for research excellence. Our core commitment is to maintain originality, significance and rigour in research within a framework of the highest standards of infrastructure, training, and integrity.

Search below for a range of research stories by department or topic. These stories include impact case studies, videos, news and the research in conversation series. For more information please see individual department websites.

Photo | Technician working in the lab, Nanoro

Malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal

Researchers from the University of Oxford and their partners have today reported findings from a Phase IIb trial of a candidate malaria vaccine, R21/Matrix-M, which demonstrated high-level efficacy of 77% over 12-months of follow-up.

Teacher marks books

Could teachers do less marking for better results?

News

The report, A Marked Improvement?,  by the University of Oxford and the charity, Education Endowment Foundation (EEF), says there needs to be more research into which marking strategies really work, but it also identifies some approaches that do make a difference.

A group of friends

Friends 'better than morphine'

News

She said: 'I was particularly interested in a chemical in the brain called endorphin.  Endorphins are part of our pain and pleasure circuitry – they’re our body's natural painkillers and also give us feelings of pleasure.  Previous studies have suggested that endorphins promote social bonding in

Photo | Glass vials for liquid samples. Laboratory equipment for dispensing fluid samples. Shallow depth of field.

Oxford vaccine reaches one billion doses released

AstraZeneca, with their extensive world-wide development and manufacturing capabilities, have been able to have the vaccine approved and licenced for use in over 170 countries, with over 20 manufacturing sites across the world, including the Serum Institute of India, working together to release t

Photo | Example of a Close-up Of A Doctor Injecting Syringe To Male Patient's Arm In Clinic

Phase I trial begins of new vaccine against the Plague

Based on the ChAdOx1 adenovirus viral vector platform also used in the successful Oxford coronavirus vaccine, forty healthy adults aged 18 to 55 will receive this new vaccine in order to assess side effects and determine how well it induces protective antibody and T cell responses.

Daily testing for students exposed to COVID-19 may be equally as effective as isolation of contacts for controlling school transmission

Daily contact COVID-19 testing for students effective at controlling transmission in schools

The independent study, sponsored by the Department of Health and Social Care and supported by the Department for Education and Office for National Statistics, ran between April and June 2021.

Photo | Elderly woman with hearing aid on grey background. Close up.

Difficulty hearing speech could be a risk factor for dementia

Hearing impairment affects around 1.5 billion individuals worldwide (World Health Organization), and there is growing evidence that this could increase the risk of dementia.

Photo | Heart shape raw meat with herbs on dark chalkboard background

Red and processed meat linked to increased risk of heart disease, Oxford study shows

Globally coronary heart diseases (caused by narrowed arteries that supply the heart with blood) claim nearly nine million lives each year1, the largest of any disease, and present a huge burden to health systems.

3D illustration of white blood cell leukocyte

T-cell ‘training grounds’ behind robust immune system response seen in adenovirus vaccines

Writing in the journal Nature Immunology, they detail an investigation into one of the key features of adenovirus vaccines – their ability to generate strong and sustained populations of the ‘killer’ T-cell element of the i

Photo | Man taking a rapid antigen test (lateral flow) for covid-19

Lateral flow tests are 95% effective at detecting Covid-19 when used at the onset of symptoms

A new study by researchers at the University of Oxford, Queen Mary University of London, Institute for Advanced Studies, Vienna, and the Medical University of Graz, has found that lateral flow tests detect Covid-19 with similar accuracy to laboratory-based PCR tests, providing they are used at th

Photo | Tray of fizzy drinks

High blood sugar levels ‘reprogramme’ stem cells

High levels of glucose in the blood ‘reprogrammes’ stem cells, leading to a lasting increase in the risk of developing dangerous atherosclerosis, according to research funded by the British Heart Foundation published today in Circulation.

lab technicians

SEREN: Improving blood-related diagnostics in sub-Saharan Africa

Impact case study

A new social enterprise is offering low-cost, easily accessible testing to diagnose blood and other diseases in sub-Saharan Africa.
children given typhoid vaccine

Influencing global policy on typhoid vaccination

Impact case study

A new vaccine, developed and evaluated in conjunction with Oxford scientists, has proved effective against typhoid, and is influencing global policy on vaccination.
European Stories logo

Uncovering Europe’s Stories

Impact case study

The Oxford University research project Europe’s Stories, led by Professor Timothy Garton Ash, aims to explore what Europeans really think about Europe, what people’s real experiences of Europe are, and what they want the EU to do by 2030.
speaker at conference

Identifying risk and building resilience in complex infrastructure systems

Impact case study

Oxford’s Environmental Change Institute has developed new modelling tools to help decision makers identify risks from climate-related infrastructure failure and build long-term resilience.
Professor Robert MacLaren

Tackling blindness through gene therapy

Impact case study

Cutting-edge gene therapies for eye diseases can help improve quality of life, extend the working lives of patients, and reduce treatment costs.
Workshop instructor showing different types of arthropod-trapping systems

Towards more equitable health research

Impact case study

A global network, coordinated by Oxford University, is helping to ensure health research benefits low-income countries.

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