Professor Paul Klenerman
Sidney Truelove Professorship of Gastroenterology, Nuffield Department of Medicine; Fellow of Green Templeton College
Infectious diseases such as HIV, hepatitis B and C, affect hundreds of millions of people worldwide. Professor Klenerman's group works on the immune response to these infections, focusing on both the host and the pathogen. As there is currently no vaccine to prevent hepatitis C infection, many of their projects have addressed aspects of chronic hepatitis C virus (HCV) infection and vaccine responses.
- Hepatitis viruses
- MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets (2015)
- Prostaglandin D2 and leukotriene E4 synergize to stimulate diverse TH2 functions and TH2 cell/neutrophil crosstalk (2015)
- A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory (2014)
Professor Klenerman has experience in TV and radio.