Professor Wordsworth trained in molecular genetics in the field of single gene disorders affecting the locomotor system. His interests include skeletal dysplasias and Marfan's disease. He has developed programmes of research into the genetic basis of inflammatory arthritis such as rheumatoid arthritis and ankylosing spondylitis. His clinical interests are in inherited disorders of the skeleton and soft tissues, inflammatory arthritis and autoimmune connective tissue diseases.
- Inflammatory arthritis e.g. rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis
- Rare inherited disorders of the skeleton and joints (skeletal dysplasias, osteogenesis imperfecta and various forms of dwarfism)
- Marfan syndrome, an inherited condition causing tall stature, fragility of the aorta and spinal deformities
- Haemochromatosis arthritis, an arthritis associated with an inherited form of iron overload
- Fibrodysplasia ossificans progressiva (FOP), an extremely rare genetic disorder that causes muscles, tendons, ligaments and other connective tissues to turn to bone
- The genetic contribution to common forms of arthritis, such as rheumatoid arthritis and ankylosing spondylitis
Professor Wordsworth has extensive media experience over two decades, including numerous radio interviews and TV news appearances. He also took part in the Channel 5 programme "The Girl Whose Muscles Were Turning To Bone", a one hour documentary that has been widely shown worldwide and repeated on numerous occasions.