Systems Approaches to Biomedical Science (EPSRC and MRC Centre for Doctoral Training) | University of Oxford
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Systems Approaches to Biomedical Science (EPSRC and MRC Centre for Doctoral Training)

About the course

The EPSRC and MRC Centre for Doctoral Training in Systems Approaches to Biomedical Science is an innovative open collaboration between the University of Oxford and 16 partner industrial organisations, working together to develop novel computational, mathematical and physical techniques to solve biomedical research problems.

This four-year programme of research and training has strong industrial links, with each student having both academic and industrial supervision.

The programme enables students from a wide range of quantitative scientific backgrounds to focus on areas of research which include the design and testing of new chemical and biological entities, modelling biological systems, and robust analysis of complex datasets. Such cross-disciplinary work introduces students to cutting edge organic chemistry, chemoinformatics, chemical and synthetic biology, biophysics, advanced computational simulation, bioinformatics, data mining, statistical analysis, physical and structural study of biomolecules, and mathematical modelling.

The CDT's industrial partners are currently AstraZeneca, Diamond Light Source, e-Therapeutics, Evotec, GE Healthcare, GlaxoSmithKline, Hoffmann La Roche, InhibOx, Lilly UK, MedImmune, Moffitt Cancer Center, Novartis, Pfizer, Structural Genomics Consortium, Sharp and UCB.

A major advantage of the programme is that you are not required to choose the substantive DPhil project until after the initial taught training phase, allowing a more informed choice of research project to be made.

The first six months of the course are devoted to acquiring advanced theoretical and technical skills that form the backbone of interdisciplinary research in this area, drawing from the engineering, mathematical, physical, chemical and biological sciences through a combination of intensive lecture courses and project work. Each taught module lasts for either one, two or three weeks and is assessed using a method appropriate to the course, for example, presentations, group assignments or assessed written work. This will be complemented with relevant research and communication skills training throughout the four-years of the programme.

After completion of the taught training phase, you will undertake two exploratory research projects of twelve weeks duration each, similar in scope to a master's-level project, followed by the substantive DPhil project. You will be based within the research group of your principal supervisor for these, which may be in the University or with an industrial partner.

Graduate destinations

The programme is part of the DTC which has a strong record of alumni success. To date, around 60% of students have gone on to pursue academic careers and 20% have entered into industrial research. The DTC’s alumni are responsible for at least 11 start-up companies and over 30 granted or pending patents. Many students who have gone onto successful careers are invited back to talk to current students within the Research Skills sessions.

Related courses

Multiple applications

In applying for this programme, you may submit further applications for up to two of the following associated programmes without paying an additional application fee.

You may only apply to one programme from Group B under this arrangement without paying further application fees.

Group A
Group B
Biomedical Imaging (EPSRC and MRC Centre for Doctoral Training)DPhil in Atomic and Laser Physics
Environmental Research (NERC Doctoral Training Partnership)DPhil in Biochemistry
Gas Turbine Aerodynamics (EPSRC Centre for Doctoral Training)DPhil in Chemical Biology
Industrially Focused Mathematical Modelling (EPSRC Centre for Doctoral Training)DPhil in Clinical Medicine
Interdisciplinary Bioscience (BBSRC Doctoral Training Partnership)DPhil in Computer Science
Partial Differential Equations (EPSRC Centre for Doctoral Training)DPhil in Condensed Matter Physics
Statistical Science (EPSRC & MRC Centre for Doctoral Training)DPhil in Engineering Science
Synthesis for Biology and Medicine (EPSRC Centre for Doctoral Training)DPhil in Inorganic Chemistry
Systems Biology (EPSRC Centre for Doctoral Training)DPhil in Molecular and Cellular Medicine
Theory and Modelling in Chemical Sciences (EPSRC Centre for Doctoral Training)DPhil in Musculoskeletal Sciences

DPhil in Organic Chemistry
DPhil in Physical and Theoretical Chemistry
DPhil in Physiology, Anatomy and Genetics
DPhil in Plant Sciences
DPhil in Statistics
DPhil in Theoretical Physics

For instructions, see Applying for more than one course in the Application Guide.

Changes to the course

The University will seek to deliver this course in accordance with the description set out in this course page. However, there may be situations in which it is desirable or necessary for the University to make changes in course provision, either before or after registration. For further information, please see our page on changes to courses.

Entry requirements for entry in 2017-18

Within equal opportunities principles and legislation, applications will be assessed in the light of an applicant’s ability to meet the following entry requirements:

1. Academic ability

Proven and potential academic excellence

Applicants are normally expected to be predicted or have achieved a first-class or strong upper second-class undergraduate degree with honours (or equivalent international qualifications), as a minimum, in physical sciences (ie chemistry, computer science, engineering, mathematics, statistics or physics) or life sciences with strong mathematical skills.

For applicants with a degree from the USA, the minimum GPA sought is 3.5 out of 4.0.

However, entrance is very competitive and most successful applicants have or are on track to obtain a first-class degree, a GPA of 3.7 or the equivalent.

If you hold non-UK qualifications and wish to check how your qualifications match these requirements, you can contact the National Recognition Information Centre for the United Kingdom (UK NARIC).

No Graduate Record Examination (GRE) or GMAT scores are sought.

Other appropriate indicators will include:

Supporting documents

You will be required to supply supporting documents with your application, including references and an official transcript. See 'How to apply' for instructions on the documents you will need and how these will be assessed.

Performance at interview(s)

Interviews are normally held as part of the admissions process for all suitably qualified applicants following initial assessment by the programme directors. Interview panels usually consist of two members, including a programme director and an academic expert in the areas relevant to the student. Interviews last for around 30 minutes and include questions and exercises to ascertain the level of mathematics obtained by the applicant to date. If necessary, interviews will be held via telephone or Skype for candidates based outside the UK.


Although publications are not required, a strong publication record may advantage an application.

Other qualifications and experience

Research or working experience in a relevant area may be an advantage. Preference may be given to those who have previously studied in a relevant area. Evidence of training in a relevant area may be an advantage.

2. English language requirement

Applicants whose first language is not English are usually required to provide evidence of proficiency in English at the higher level required by the University.

3. Availability of supervision, teaching, facilities and places

The following factors will govern whether candidates can be offered places:

  • The ability of the Centre for Doctoral Training to provide the appropriate supervision, research opportunities, teaching and facilities for your chosen area of work
  • Minimum and maximum limits to the numbers of students who may be admitted to Oxford's research and taught programmes.

The provision of supervision, where required, is subject to the following points:

  • The allocation of graduate supervision is the responsibility of the Centre for Doctoral Training and it is not always possible to accommodate the preferences of incoming graduate students to work with a particular member of staff
  • Under exceptional circumstances a supervisor may be found outside the Centre for Doctoral Training.

In the first year of the course, students will be supervised by the programme directors, who will also support students in choosing their doctoral research project. Supervision arrangements for years two to four will therefore be confirmed at the end of the first year when the doctoral project is chosen.  

Where possible your academic supervisor will not change for the duration of the doctoral research phase of your course (years two to four), however it may be necessary to assign a new academic supervisor for reasons which might include sabbatical leave, maternity leave or change in employment.

4. Disability, health conditions and specific learning difficulties

Students are selected for admission without regard to gender, marital or civil partnership status, disability, race, nationality, ethnic origin, religion or belief, sexual orientation, age or social background.

Decisions on admission are based solely on the individual academic merits of each candidate and the application of the entry requirements appropriate to the course.

Further information on how these matters are supported during the admissions process is available in our guidance for applicants with disabilities.

5. Assessors

All recommendations to admit a student involve the judgment of at least two members of academic staff with relevant experience and expertise, and additionally must be approved by the Director of Graduate Studies or Admissions Committee (or equivalent departmental persons or bodies).

Admissions panels or committees will always include at least one member of academic staff who has undertaken appropriate training.

6. Other information

Whether you have yet secured funding is not taken into consideration in the decision to make an initial offer of a place, but please note that the initial offer of a place will not be confirmed until you have completed a Financial Declaration.


The taught component of the programme is held within the University of Oxford Doctoral Training Centre (DTC). The DTC provides excellent facilities specifically designed to promote interdisciplinary study and currently houses six programmes with multiple seminar rooms available. All students have individual study spaces with access to a desktop computer and appropriate IT support. Social break-out space is provided and there is a small well-stocked library.

The DTC provides opportunities for all cohorts to come together regularly for both academic and social purposes.

The short projects and DPhil projects are hosted in a range of departments across the University or with the industrial collaborator, as appropriate.  


There are over 1,000 full graduate scholarships available across the University, and these cover your course and college fees and provide a grant for living costs. If you apply by the relevant January deadline and fulfil the eligibility criteria you will be automatically considered. Over two thirds of Oxford scholarships require nothing more than the standard course application. Use the Fees, funding and scholarship search to find out which scholarships you are eligible for and if they require an additional application, full details of which are provided.

This programme has a dedicated stream of funding, and the majority of students on the programme are funded. Eligibility restrictions apply. Further details can be found on the dCDT webpage.


Annual fees for entry in 2017-18

Fee status

Tuition fee

College fee

Total annual fees

(including Islands)
c. £4,250£3,021c. £7,271

The fees shown above are the annual tuition and college fees for this course for entry in the stated academic year; for courses lasting longer than one year, please be aware that fees will usually increase annually. For details, please see our guidance on likely increases to fees and charges.

Tuition and college fees are payable each year for the duration of your fee liability (your fee liability is the length of time for which you are required to pay tuition and college fees).

Following the period of fee liability, you may also be required to pay a University continuation charge and a college continuation charge. The University and college continuation charges are shown on the Continuation charges page.

For more information about tuition fees, college fees and fee liability, please see the Fees section of this website. EU applicants should refer to our dedicated webpage for details on the impact of the result of the UK referendum on its membership of the European Union.

Additional information

There are no compulsory elements of this programme that entail additional costs beyond fees and living costs.  However, please note that, depending on your choice of research topic and the research required to complete it, you may incur additional expenses, such as travel expenses, research expenses, and field trips. You will need to meet these additional costs, although you may be able to apply for small grants from your department and/or college to help you cover some of these expenses.

Living costs

In addition to your tuition and college fees, you will need to ensure that you have adequate funds to support your living costs for the duration of your course.

For the 2017-18 academic year, the range of likely living costs is between £1,002 and £1,471 for each month spent in Oxford. Full information, including a breakdown of likely living costs in Oxford for items such as food, accommodation and study costs, is available on our Living costs page.

How to apply

Before making a formal application for the programme you are encouraged to submit an up-to-date CV for assessment to the contact details provided on this page.

You are not expected to make contact with an academic member of staff before you apply.

The set of documents you should send with your application to this course comprises the following:

Official transcript(s)

Your transcripts should give detailed information of the individual grades received in your university-level qualifications to date. You should only upload official documents issued by your institution and any transcript not in English should be accompanied by a certified translation.

More information about the transcript requirement is available in the Application Guide.


A CV/résumé is compulsory for all applications. Most applicants choose to submit a document of one to two pages highlighting their academic achievements and any relevant professional experience.

Statement of purpose/personal statement:
1,000 words

The statement should be in English and written in the form of an essay. Your proposal should explain your motivation for applying for the course at Oxford, your relevant experience and education, and the specific areas that interest you and/or you intend to specialise in. 

It is not necessary to provide a detailed information on your proposed research, but you should give a brief description of the area in which you wish to carry out research. This need not be specific if you have not yet decided on your preferred topic or area. 

This will be assessed for your research interests and your reasons for applying to the course, as well as how your background and experience relates to the area of systems approaches to biomedical science. It will also be assessed for coherence, evidence of motivation and understanding of the proposed area of study.

References/letters of recommendation:
Three overall, academic preferred

Whilst you must register three referees, the department may start the assessment of your application if two of the three references are submitted by the course deadline and your application is otherwise complete. Please note that you may still be required to ensure your third referee supplies a reference for consideration.

One professional reference can be accepted if you have relevant work experience, but academic references are preferred.

Your references will support intellectual ability, academic achievement, motivation and ability to work in a group.