Professor Wood researches gene therapy for degenerative disorders of the nervous system and muscle. His research focuses on new therapeutic approaches, targeting messenger RNA. This has the potential to allow us to repair genetic defects and target the specific genes which cause diseases such as Duchenne muscular dystrophy. He also investigates the ways RNA interference, or RNAi, could be used to "silence" genes which cause disease, both in muscle and in the nervous system. In particular, RNAi has great potential for use in treating neurodegenerative disorders such as Parkinson’s disease.
He has been an advisor to the Gene Therapy Advisory Committee, UK, and scientific advisor to Parkinson's UK, Action Duchenne, Muscular Dystrophy Campaign, Novartis, and Sirna Therapeutics.
- Gene therapy
- RNA-based therapy
- Brain drug delivery
- Exosome therapy and technology
- Neurodegenerative disease
- Parkinson's disease, Alzheimer's disease, Huntington's disease
- Muscle degenerative disease, Duchenne muscular dystrophy
Professor Wood has considerable media experience including radio and television interviews for the BBC and other outlets, as well as appearances in print.