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More fruit and veg lowers heart risk
Source: European Heart Journal
19 Jan 11
People who eat more fruit and vegetables have a lower risk of dying from the most common form of heart disease, an Oxford University-led study has found.
However, the researchers point out in the European Heart Journal that a higher fruit and vegetable intake occurs among people with other healthy eating habits and lifestyles, and that these factors could also be associated with the lower risk of dying from ischaemic heart disease.
Ischaemic heart disease (IHD) is one of the leading causes of death in Europe and is characterised by reduced blood supply to the heart. People suffering from it can develop angina, chest pains and have a heart attack.
The team analysed data from the European Prospective Investigation into Cancer and Nutrition (EPIC) Heart study. They showed that people who ate at least eight portions of fruit and vegetables a day had a 22% lower risk of dying from IHD than those who consumed fewer than three portions a day.
A portion weighed 80 g, equal to a small banana, a medium apple, or a small carrot.
Dr Francesca Crowe of the Cancer Epidemiology Unit at the University of Oxford, and the first author of the paper by the EPIC study collaborators, said: ‘This study involved over 300,000 people in eight different European countries, with 1,636 deaths from IHD.
‘It shows a 4% reduced risk of dying from IHD for each additional portion of fruit and vegetables consumed above the lowest intake of two portions. In other words, the risk of a fatal IHD for someone eating five portions of fruit and vegetables a day would be 4% lower compared to someone consuming four portions a day, and so on up to eight portions or more.’
Dr Francesca Crowe
The risk of a fatal IHD for someone eating five portions of fruit and vegetables a day would be 4% lower compared to someone consuming four portions a day, and so on up to eight portions or more
The EPIC study started in 1992 and recruited participants until 2000 from a total of 10 European countries that included the UK. For the analysis of IHD deaths, data from eight countries for people aged between 40 and 85 were used. Data from France and Norway were excluded due to the small number of IHD deaths over the course of the trial.
Participants answered questions about their diet at the time of entry to the study and other questions about health, socio-economic status and life-style, such as smoking, drinking and exercise habits. They were followed-up for an average of nearly eight and a half years.
The researchers found that the average intake of fruit and vegetables was five portions a day; people in Greece, Italy and Spain ate more, and those in Sweden ate less.
When analysing the data, the researchers made allowances for confounding factors such as differences in lifestyles and eating habits. However, the study could be limited by errors in measuring correctly people’s fruit and vegetable intake as well as other aspects of their diet. In addition, the study had a higher proportion of women, which might not be generalisable to the wider European population.
Dr Crowe said: ‘The main message from this analysis is that, in this study, people who consume more fruits and vegetables have lower risk of dying from IHD. However, we need to be cautious in our interpretation of the results because we are unsure whether the association between fruit and vegetable intake and risk of IHD is due to some other component of diet or lifestyle.
‘If we could understand, by means of well-designed intervention studies, the biological mechanisms that could underlie the association between fruits and vegetables and IHD, this might help to determine whether or not the relation between fruit and vegetables with IHD risk is causal.’
Professor Sir Michael Marmot of University College London and chairman of the Commission on Social Determinants of Health, writes in an accompanying editorial, that it is difficult to reach firm conclusions about causation from results that show a 22% lower risk of dying from IHD (an odds ration of 0.78) in people who eat eight portions of fruit and vegetables a day.
‘Such an odds ratio is, however, of huge practical importance,’ he continues. ‘Cardiovascular disease is the most common cause of death. A reduction of 22% is huge.
‘But ... this reduction in mortality comes with consumption of eight portions a day, or 640g. Such a high consumption was found in only 18% of the men and women in these eight cohorts. There would need to be big shift in dietary patterns to achieve this healthy consumption of eight portions a day. It is worth trying to move in that direction. Reductions in cancers of several sites, in blood pressure and stroke, would add to this reduction in fatal CHD. Moving to a diet that emphasises fruit and vegetables is of great importance to public health.’