Staying well after depression

5 November 2008

The comedian, Ruby Wax has recently revealed how she has learnt to cope with depression by practicing 'mindfulness', an approach that integrates modern therapy with ancient meditation practices. For Ruby, mindfulness was an important element in her cure.
Oxford University, along with the University of Bangor, is now conducting a clinical trial of mindfulness and another similar approach to assess how effective these therapies are in people with recurrent depression. Both centres are recruiting participants to take part in the trials.
Ruby Wax has been so impressed with the difference made to her life by mindfulness that she is now herself a mindfulness practitioner and trainer.
‘Under stress the only way I can reduce my anxiety, both physically and mentally, is by practising mindfulness. My heart rate lowers, I can breathe again and my mind becomes clear so I can deal more effectively with the situation.’
Professor Mark Williams at Oxford University has spent many years developing effective ways of assisting people with recurrent depression and suicidality.
‘Sir Winston Churchill famously described it as his “black dog”: depression can be a recurrent illness. People who have had one major attack of depression are more likely to experience further episodes. Our research, however, has shown that people can learn skills to stay well. The key things are to see the warning signs early enough, then to be able to stand back from the whirlpool of negative thoughts and feelings so you do not get sucked into it. It takes some effort to learn how best to do this, but it can be done.’
Over 300 people are being recruited to take part in the trial, with half the number to be recruited in Oxfordshire and half in North Wales. Some will take part in the mindfulness programme, while others will receive an alternative group therapy. This will enable the researchers to see what elements of the approach are most helpful. A third group will wait for treatment, then choose which treatment they’d like to have.
Mindfulness-based cognitive therapy brings together modern cognitive behaviour therapy with the ancient practice of mindfulness meditation. Participants will be given classes that include meditation learning, education about depression, and advice on how best participants can look after themselves when their feelings threaten to overwhelm them.
‘The way in which we react to stressful or emotional situations we face can cause further stress,’ explains Rebecca Crane, Director of Training at Bangor University's Centre for Mindfulness Research and Practice. ‘Mindfulness is effective in reducing this extra layer of difficulty and struggle. When practiced by people with chronic pain, for example, the acceptance of pain reduces the struggle we experience around the pain and so reduces stress. This can often have the effect of reducing the actual experience of the pain.’
‘We know that in people with depression, fear of the return of depression can create a way of reacting to feelings of sadness which feeds the downward spiral into depression. Mindfulness helps individuals to see clearly and accept the state of mind that they are in and to respond rather than react to it. In this way it can become possible to step out of the ‘loops’ we get caught up in,’ she adds.
Those interested in participating in the trial should contact Dr Ruth Collins for further information on 01865 226468.
For more information please contact the Press Office, University of Oxford on +44 (0)1865 280530 or press.office@admin.ox.ac.uk.  

Notes for Editors

  • The trial aims to recruit people who have been depressed more than three times – twice in the past five years and at least once in the last two years – who are currently in remission or recovery from major depression, and not taking antidepressants at the moment. People will be randomly allocated to standard treatment; to an eight-week cognitive psycho-educational course, which teaches participants new ways of handling difficult thoughts and feelings and how best to look after themselves when their feelings threaten to overwhelm them; or to mindfulness-based cognitive therapy. Effects on rates of relapse and rates of suicidal symptoms in those who relapse will be assessed over a period of 12 months following treatment.
  • Clinical depression affects one in four people at some point during their lives. Fifty per cent of people who have recovered from one episode of depression experience another episode within the following two years. Risk of relapse increases with the number of previous episodes: probability of relapse in those who have suffered from three or more previous episodes has been found to be 80 per cent.
  • Suicide and attempted suicide (now usually termed ‘deliberate self-harm’) are major problems in most countries in the world. In the UK alone there are approximately 5,000 suicides per year, considerably more than deaths following road traffic accidents, and more than 170,000 people attending hospital having deliberately harmed themselves.
  • Oxford University psychologists are also beginning a separate trial in the Oxford area to examine whether mindfulness-based cognitive therapy can benefit those suffering significant distress through health anxiety. Those interested in participating in this different trial should contact the Oxford Mindfulness Centre for further information on 01865 613143 or freda.mcmanus@psych.ox.ac.uk.
  • The Centre for Mindfulness Research and Practice at Bangor University and Oxford Mindfulness Centre are committed to the relief of suffering and the promotion of wellbeing through the application of mindfulness-based approaches. This is carried through by teaching the general public, training professionals and researching the clinical applications of mindfulness.
  • Oxford University’s Medical Sciences Division is one of the largest biomedical research centres in Europe. It represents almost one-third of Oxford University’s income and expenditure, and two-thirds of its external research income. Oxford’s world-renowned global health programme is a leader in the fight against infectious diseases (such as malaria, HIV/AIDS, tuberculosis and avian flu) and other prevalent diseases (such as cancer, stroke, heart disease and diabetes). Key to its success is a long-standing network of dedicated Wellcome Trust-funded research units in Asia (Thailand, Laos and Vietnam) and Kenya, and work at the MRC Unit in The Gambia. Long-term studies of patients around the world are supported by basic science at Oxford and have led to many exciting developments, including potential vaccines for tuberculosis, malaria and HIV, which are in clinical trials.* Bangor University has a strong research base across a spectrum of academic disciplines engaging in research at national and international levels and continues to develop academic specialisms which have a world-wide impact. The University provides strong support for research activities including encouraging links with commercial and industrial bodies in the UK and overseas. The University also aims to be responsive to local and regional needs and is particularly conscious of its role as a research resource and a training base for North Wales.