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Cardiovascular Medicine

Research programmes

DPhil in Cardiovascular Medicine

Course Code | 001770

This three-year research-based DPhil programme is aimed at clinicians and basic scientists with an interest in pursuing research in the cardiovascular field.

Subject areas cover the entire spectrum of basic and clinical cardiovascular research, including:

  • Molecular genetics and molecular biology of heart muscle disease
  • The role of tetrahydrobioterin in the regulation of endothelial nitric oxide synthase activity in vascular disease
  • Genetic and molecular mechanisms in heart development
  • Heart failure, atrial fibrillation and calcium signalling: role of nitric oxide and reactive oxygen species
  • The role of nitric oxide and superoxide in the early endothelial dysfunction characteristic of pre-atherosclerotic states
  • Development and application of Magnetic Resonance Imaging and spectroscopy to characterize atherosclerosis and cardiovascular disease
  • The molecular basis and population genetics of common human inherited cardiovascular traits and diseases.
  • Cardiovascular imaging and early development of cardiovascular disease
  • The role of cardiac energetics in the pathogenesis of heart failure
  • High throughput screening to identify key genetic pathways that mediate cardiovascular disease and identification and validation of novel druggable targets within these pathways

How to Apply

The deadlines for this course are 16 November 2012, 4 January 2013 and 8 March 2013. Deadlines for studentship applications will be notified at time of advertisement

The standard set of materials you should send with any application to a research course comprises:

The research proposal for applicants to the DPhil in Cardiovascular Medicine should normally be two pages in length, covering areas such as the background to the research, methodology, expected results and the contribution to the field of learning.

Please follow the detailed instructions in the Application Guide, and consult the Cardiovascular Medicine website for any additional guidance.

Academic resources

Research will be undertaken in state-of-the-art laboratories at the Wellcome Trust Centre for Human Genetics, the West Wing of the John Radcliffe Hospital site, the Cardiovascular Clinical Research Facility (CCRF), or in the Oxford Centre for Clinical Magnetic Resonance Research (OCMR).

The University's department of Cardiovascular Medicine is one of five units comprising the Radcliffe Department of Medicine. The department also has close links with the NHS Cardiac Clinical Centre, providing access to patients and resources appropriate to all areas of clinical cardiovascular investigation. Close links are also maintained with the Clinical Trials Service unit, which continues to provide first-class expertise in clinical epidemiology.

An award was made to the University by the British Heart Foundation in order to establish a Centre of Research Excellence (CRE) to enable further research into cardiovascular disease; the BHF CRE brings together thirty-six world-leading clinical and laboratory researchers, based in ten University departments and centres.

Professor Hugh Watkins, Head of the Department of Cardiovascular Medicine, is Director of this CRE, and some of the CRE funding is deployed to support DPhil students.

Academic staff profiles

Information on academic staff profiles External link

Graduate destinations

Most graduates continue in academic research or move into clinical medicine.

Related programmes

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www.cardiov.ox.ac.uk

Director of Graduate Studies
+44 (0) 1865 287601
martin.farrall@cardiov.ox.ac.uk

 

 

 


Main areas of research interests

Research interests on the Cardiovascular Medicine website External link

 

Entry requirements

Applicants should have BSc (minimum grade of an upper 2:1 class or above), or a medical degree and some specialist experience, though not necessarily in cardiology specifically

 

Clinical applicants will typically have obtained MRCP or equivalent, though not CCT or consultant status

 

Selection criteria

Selection criteria on the Cardiovascular Medicine website External link

 

English language requirements

Higher level


Funding/awards

Details of available funding on the Cardiovascular Medicine website External link

 

Number of applicants
2012/13

10


Number of places available
2013/14

7

 

Statement of Provision

Cardiovascular Medicine - Research External link